X-chromosome variants help explain autism’s sex bias | Spectrum | Autism Research News
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
Scans of sundry variant types uncover autism-linked genes | Spectrum | Autism Research News
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.
Mutations disrupting chromatin interactions contribute to autism | Spectrum | Autism Research News
The mutations occur spontaneously in noncoding stretches of DNA that control gene expression.
The final frontier: Autism geneticists take on the noncoding genome | Spectrum | Autism Research News
The vast stretches of DNA that don't code for proteins could fill key knowledge gaps about autism genetics. But making sense of it all won't be easy.
Common inherited variants tied to autism show sex bias in families | Spectrum | Autism Research News
Siblings of autistic females are more likely to have autism than siblings of autistic males are, and mothers of autistic children carry more common, autism-linked variants than fathers do.
Spectrum of variants contribute differently to autism traits | Spectrum | Autism Research News
Different combinations of common, rare, inherited and spontaneous mutations may explain why traits vary so widely among autistic people.
Novel gene linked to brain size in autistic people | Spectrum | Autism Research News
The gene, YTHDF2, may be one of several that contribute to an autism subtype marked by an unusually big brain.
Autism-linked genetic variants increase, decrease intelligence | Spectrum | Autism Research News
Common and rare variants in or near autism-associated genes can have opposite effects on cognition.
Analysis ups estimate of spontaneous mutations’ role in autism | Spectrum | Autism Research News
Spontaneous genetic mutations contribute to autism in 30 to 39 percent of all people with the condition, and 52 to 67 percent of autistic children whose siblings do not also have the condition.
Mutations in the noncoding genome contribute to autism | Spectrum | Autism Research News
Spontaneous mutations in parts of the genome that regulate gene EBF3 appear to contribute to autism risk.
Autism News International