CHD8 mutation in 33 mouse strains yields range of traits | Spectrum | Autism Research News
The findings put genetic background forward to help explain autism’s heterogeneity.
Excess of ‘don’t eat me’ cell signals may drive brain enlargement in autism | Spectrum | Autism Research News
The signal, called CD47, is disrupted in autistic people who have a larger-than-average head.
Zebrafish point to new gene involved in brain overgrowth, autism | Spectrum | Autism Research News
The gene, YTHDF2, has not previously been linked to autism.
New diagnostic code for PTEN syndrome may spur research | Spectrum | Autism Research News
The code may help scientists identify people with the autism-linked condition and recruit them into clinical trials.
Different forms of autism have opposite problems with brain precursor cells | Spectrum | Autism Research News
The cells’ altered proliferation rates hint at ways to diagnose and potentially treat autism earlier.
Novel gene linked to brain size in autistic people | Spectrum | Autism Research News
The gene, YTHDF2, may be one of several that contribute to an autism subtype marked by an unusually big brain.
Organoids show how mutations in top autism gene may lead to brain overgrowth in people | Spectrum | Autism Research News
The loss of CHD8, a top autism gene, speeds up the production of certain neurons and leads to overgrowth in spheres of cultured brain cells.
Three autism-linked genes converge on tweaks to cells’ timing | Spectrum | Autism Research News
Mutations in all three accelerate the maturation of inhibitory neurons, which could upset the brain’s balance of excitation and inhibition early in development.
Null and Noteworthy: Null rejection, repetitive behaviors, unsuccessful treatments | Spectrum | Autism Research News
In this edition of Null and Noteworthy, tests of intranasal oxytocin and an Angelman syndrome treatment fail to see results.
Autism News International