Show threadChuck DarwinSep 3, 2023

@jparcoeur @skralyx

"It seems we’ve reduced the vague and complicated “young blood” effect down to just one factor.

"Clinical trials have got to be just around the corner.

"Hey, by the time #PF4 is available as a medication, I might even still remember how to get to the drugstore."

https://www.dailykos.com/stories/2023/8/18/2187800/-Three-independent-studies-say-that-blood-platelet-factor-PF4-prevents-and-reverses-cognitive-decline

Three independent studies say that blood platelet factor PF4 prevents and reverses cognitive decline

Although the percentage of older people with dementia is thankfully decreasing, from 13% to 10% in those over 70 from 2011-2019, the absolute number of people with dementia is actually increasing. That’s because the share of the U.S. population that is...

Daily Kos
katch wreckAug 18, 2023

`... its effects on the immune system also led to changes in the #brain, probably through indirect mechanisms. Old mice that received doses of #PF4 showed decreases in damaging #inflammation in the #hippocampus — a part of the brain that’s particularly vulnerable to the effects of ageing. They also showed increases in the levels of molecules that promote #synaptic plasticity (the capacity to alter the strength of connections between nerve cells).`

https://www.nature.com/articles/d41586-023-02563-z

Older mouse brains rejuvenated by protein found in young blood

A platelet factor joins the list of blood components that might have anti-ageing effects.

innovation2Aug 17, 2023

Turning the tap on the Fountain of Youth? Restoring youth to old brains with PF4 https://innovationtoronto.com/2023/08/turning-the-tap-on-the-fountain-of-youth-restoring-youth-to-old-brains-with-pf4/

#UCSF #klotho #PF4 #FountainofYouth

Turning the tap on the Fountain of Youth? Restoring youth to old brains with PF4

Innovation Toronto