`... its effects on the immune system also led to changes in the #brain, probably through indirect mechanisms. Old mice that received doses of #PF4 showed decreases in damaging #inflammation in the #hippocampus — a part of the brain that’s particularly vulnerable to the effects of ageing. They also showed increases in the levels of molecules that promote #synaptic plasticity (the capacity to alter the strength of connections between nerve cells).`

https://www.nature.com/articles/d41586-023-02563-z

Older mouse brains rejuvenated by protein found in young blood

A platelet factor joins the list of blood components that might have anti-ageing effects.