Can cells break the laws of thermodynamics?
Our preprint investigates the current scientific controversy. Using our nanosensor, we addressed unexpected artifacts and measured temperature with record accuracy inside cells.
https://www.researchsquare.com/article/rs-6074308/v1
The remarkable work from P. Maurer's lab also independently reports similar artifacts.
https://arxiv.org/abs/2503.20816
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Investigating intracellular heating rates with millikelvin nanothermometry

Nanothermometry within living cells is an important endeavour in physics,as the mechanisms of heat diffusion in such complex and dynamic environments remain poorly understood. In biology, nanothermometry may offer new insights into cellular biology and open new avenues for drug-discovery. Previou...