π For #ECPR as for all patients keep on caring & keep on analyzing! Initial lactate can indicate higher burden of ischemia prior to #ECMO, with subsequent clearance determined by relationship between lactate catabolism vs generation. Neurologic survival advantage if adequate #extracorporeal BF/catabolic function & no longer ischemia. Pts who fail to rapidly clear lactate warrant evaluation for: ongoing ischemia or insufficient #ECLS
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