"Please read the IPC report, cover to cover. Read it in sorrow and in anger. Not as words and numbers but as names and lives. Be in no doubt that this is irrefutable testimony.

"It is a famine. The Gaza Famine.

"It is a famine that we could have prevented, if we had been allowed. Yet food stacks up at borders because of systematic obstruction by Israel.

"It is a famine within a few hundred metres of food, in a fertile land.

"It is a famine that hits the most vulnerable first. Each with a name, each with a story. That strips people of dignity before it strips them of life. That forces a parent to choose which child to feed. That forces people to risk their lives to seek food.

"It is a famine that we repeatedly warned of. But that the international media has not been allowed in to cover. To bear witness.

"It is a famine in 2025. A 21st century famine watched over by drones and the most advanced military technology in history.

"It is a famine openly promoted by some Israeli leaders as a weapon of war."

โ€”#TomFletcher, UN Relief Chief at the Office for the Coordination of Humanitarian Affairs #OHCA, comments at the publication of the major #IPC report confirming conclusively that there is #famine in #Gaza, 22nd Aug 2025

https://www.unocha.org/news/un-relief-chief-says-gaza-famine-must-spur-world-urgent-action
#GazaIsBeingStarved #CrimesAgainstHumanity

Head computed tomography & neuroprognostication after out-of-hospital cardiac arrest
๐Ÿ” international multicentre study within TTM2 trial including
140 unconscious patients
โ˜ข๏ธ routine CTs obtained >48 h โ‰ค7 days post-CA
๐Ÿง  standardised qualitative/quantitative assessments of head CT reliable and feasible methods to predict poor functional outcome after #OHCA; automated vs to manual ratings + make head CT quantification more accessible to all centres treating CA
๐Ÿ”“ https://rdcu.be/dLEHN
Standardised and automated assessment of head computed tomography reliably predicts poor functional outcome after cardiac arrest: a prospective multicentre study

๐Ÿš‘ ๐Ÿš Prehospital ground & helicopter-based #ECPR reduce barriers to #extracorporeal support, potentially improving #OHCA survival rates! Geographic Information System model to estimate transport times & number of #ECLS eligible patients within the United States. The study demonstrates a 2-fold increase in #ECMO eligibility for field-deployable ground-based system + 4-fold increase for HEMS-based system vs to current hospital-based system.
๐Ÿ–‡๏ธ https://bit.ly/4bEE0TK
Approach to #ECPR in children, narrative review by pediatric ECPR working group of Euro ELSO:
๐Ÿšจ conventional #CPR
๐Ÿฉธ potential benefits of #ECMO in #resuscitation
๐Ÿง  survival & neurological outcome
๐Ÿฅ #ECLS for intra-hospital cardiac arrest #IHCA
๐Ÿš‘ ECLS for out-of-hospital cardiac arrest #OHCA
๐Ÿ”ฎ future directions
Open access #FOAMcc #FOAMecmo #PedsICU
๐Ÿ”“ https://bit.ly/3wcJu9d
From the #EuroELSO2024 Perfusion special issue
๐Ÿ”“ journals.sagepub.com/toc/prfa/39/1_suppl
#Extracorporeal versus conventional #CPR in out-of-hospital & in-hospital cardiac arrest, updated meta-analysis & trial sequential analysis (2000-Oct 2023, 13 RCTs/PSMs included):
๐Ÿซ€ #ECLS significantly reduces in-hospital mortality, improving 30-day survival & neurological outcome
๐Ÿซ€ recent studies revealed newly significant decrease in mortality in #OHCA
Open access #FOAMcc #FOAMecmo
๐Ÿ”“ https://rdcu.be/dzmpV
Extracorporeal cardiopulmonary resuscitation versus conventional CPR in cardiac arrest: an updated meta-analysis and trial sequential analysis | Critical Care

Challenge for the ones of you used to #ECMO support
๐Ÿซ€62y, refractory VFib #OHCA in the ED
๐Ÿฉธextracorporeal cardiopulmonary resuscitation initiation
Which kind of cannulation was performed to provide veno-arterial #ECLS??
#FOAMcc #FOAmecmo on @ICM
๐Ÿ“ธ https://rdcu.be/dy588
Arterial graft cannulation for extracorporeal cardiopulmonary resuscitation

๐Ÿง  Early methylprednisolone in comatose #OHCA patients: may improve outcome?? STEROHCA RCT on ๐Ÿš‘ prehospital single high-dose IV (250 mg) vs placebo
Full results #FOAMcc on @ICM
๐Ÿ”“ https://rdcu.be/dqJU7
Editorial
๐Ÿ”“https://rdcu.be/drREl
โฌ‡๏ธ Below visual abstract
Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

โ€œ#FIFA has made a public statement reporting no notable increase in #SCAD based on the official FIFA registry. A recent Australian study investigating the prevalence of out-of-hospital cardiac arrest (#OHCA) following #COVID19 infection and vaccination in over 4million young individuals demonstrated no increase in OHCA rates or #myocarditis as a contributing factor to OHCA.โ€

๐Ÿ”ฅ Should we give steroids after #OHCA? The pathophysiology of post-cardiac arrest syndrome
features ischaemic/reperfusion injury & release of high levels of inflammatory cytokines. If early reperfusion causes release of inflammatory mediators, it would make sense to provide anti-inflammatory agents as soon as possible after ROSC (even if anti-inflammatory targets are not key to improving neuro-outcomes).
Editorial
๐Ÿ”“ https://rdcu.be/drREl

Refers to STEROHCA ๐Ÿ‡ฉ๐Ÿ‡ฐ RCT
๐Ÿ”“ https://rdcu.be/dqJU7

Should we give steroids after out-of-hospital cardiac arrest?