jobRxivMar 11, 2024

Research Associate in Cancer Biology @ERainero_lab

School of Biosciences, University of Sheffield

A 3 year postdoc position is available to work on a Breast Cancer Now funded project investigating integrin-dependent #ECMatrix trafficking.

See the full job description on jobRxiv: https://jobrxiv.org/job/school-of-biosciences-university-of-sheffield-27778-research-a...
https://jobrxiv.org/job/school-of-biosciences-university-of-sheffield-27778-research-associate-in-cancer-biology/?feed_id=72813

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jobRxivFeb 23, 2024

Research Associate in Cancer Biology @ERainero_lab

School of Biosciences, University of Sheffield

A 3 year postdoc position is available to work on a Breast Cancer Now funded project investigating integrin-dependent #ECMatrix trafficking.

See the full job description on jobRxiv: https://jobrxiv.org/job/school-of-biosciences-university-of-sheffield-27778-research-a...
https://jobrxiv.org/job/school-of-biosciences-university-of-sheffield-27778-research-associate-in-cancer-biology/?feed_id=71945

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ERainero_labFeb 13, 2024
📢 We are recruiting!!! 📢
A 3 year postdoc position is available in my lab to work on a
@BreastCancerNow funded project investigating integrin-dependent #ECMatrix trafficking.
Closing date: 12th March
Apply 👇
https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_posting_apply?PARAM=cG9zdF9pbnN0X2d1aWQ9NjVDQTkwQTA1M0MxMjBDMkUxMDAwMDAwQUMxRTg4NzgmY2FuZF90eXBlPUVYVA%3d%3d&sap-client=400&sap-language=EN&sap-accessibility=X&sap-ep-themeroot=%2fSAP%2fPUBLIC%2fBC%2fUR%2fuos#
RT and DM for more info
@MCB_Sheffield
@TUOS_Cancer
Data Overview: Job Posting

Show threadERainero_labJan 15, 2024
#ECMatrix is internalised during cell migration and p38/PP2/a2 are required for cell migration and invasion (5/6)
Show threadERainero_labJan 15, 2024
A while ago
@johannaivaska
showed that p38 is activated by a2 integrin upon collagen binding.
@KeqianN
found the a2 is required for #ECMatrix uptake (4/6)
Show threadERainero_labJan 15, 2024
She performed a kinome and phosphatome RNAi screen and identified p38 MAPK and the phosphatase PP2 subunit PPP2R1A as novel regulators of #ECMatrix uptake (3/6)
Show threadERainero_labJan 15, 2024
In collaboration with
@fred_bard, @Montse_Llanses developed a high-throughput assay to visualise and quantify #ECMatrix uptake (2/6)
ERainero_labJan 15, 2024
New preprint from our lab, by
@Montse_Llanses, @KeqianN,
@ZheBao_Sheff, @RacheleBacchet1,
@ShengnanYuan and
@jtyler91: internalisation of integrin-bound #ECMatrix modulates invasive carcinoma cell migration https://biorxiv.org/content/10.1101/2024.01.11.575153v1 (1/6)
JanGebauerApr 27, 2022
Sorry, but I am just missing my favourite topics as hashtags, have to change that
#Collagen
#StructuralBiology
#ProteinCrystllography
#ECMatrix
I know they will live a lonely live 😜 Probably the one and only mention ... but someone has to care for them😉