Good things: I had to go to the dentist this week. As I was waiting for my appointment wearing an N95 mask, the dentist peered into the waiting room to tell me she was almost done. She was also wearing an N95 mask, a 3M Aura!

Then a few minutes later she walked out again with the patient ahead of me, and that person was also wearing an N95! Three of us in one room with N95s out in the wild and not at a special masked event, it's been a while since I've experienced that!

#WearAMask #MaskUpN95 #Covid #CovidIsNotOver

RE: https://disabled.social/@ahimsa_pdx/116423791927971235

Boosting for the morning folks 😊

@mecfs @longcovid

#USPol #LongCovid #MEcfs #POTS #CovidIsNotOver #FundLongCovid #MedMastodon

Bei der Frequenz, wie hier derzeit Rettungswagen durch den Stadtteil und die Straße brausen könnte man fast denken, die fahren mittlerweile auch Pakete für Amazno aus … (könnte bittere Ironie enthalten)

Im Ernst, was ist da los? Das geht hier gefühlt so seit der strenge Winter vorbei ist.

#CovidIsNotOver #MedizinBrennt #gesundheitsnotstand #are #ili #rsv

RE: https://disabled.social/@tomkindlon/116417351897995176

This study https://www.tandfonline.com/doi/full/10.1080/17501911.2026.2656361 passes lots of hurdles:

this is one of the few epigenetic studies to analyze persistent genome-wide DNAm in longitudinally matched samples across COVID-19 and Long-COVID phenotypes, including targeted assessment of the contributions of genes on the X chromosome

And some of their findings are encouraging; they found no sign of increased epigenetic pace of aging in pre-COVID loci.

That's no guarantee on that front though; epigenetic clocks may not be causally harmful, there are surely other as-yet unidentified loci, and there may be epigenetic changes at a small set of loci causally tied to Long COVID - remember a single methylation can in some conditions drastically alter expression - but it's quite encouraging.

And I want to be happy and positive about their other findings, but really I'm happiest about the fact they do their job as scientists and point out what you might have guessed:

The Illumina EPIC V2 array interrogates only a small fraction of the estimated 28 million CpG sites in the human genome, and while many of these are in regulatory regions, it is estimated that up to 80% of CpGs are constitutively methylated and may not have any regulatory relevance. Moreover, the methylome is highly correlated within individuals, meaning that subtle or localized changes could be missed in genome-wide analyses

Their estimates of cell-type composition were coarse (only 6 types, no Tn measure) and as expected for that coarseness there's no sign of pathology.

#COVID #COVID19 #SARSCoV2 #CovidIsNotOver

Study links long COVID in kids to worse grades, attention, and social life

Children and adolescents with long COVID are significantly more likely to experience worsening grades, difficulty concentrating, and having limited fun with friends, according to a new study published in Academic Pediatrics.

“Given that both educational performance and positive peer interactions are key developmental tasks among both school-age children and adolescents, our findings demonstrate important functional impairments that extend beyond the clinical symptomatology that has been described to date,” the researchers write. “Such impairments of desirable child developmental experiences may have long-term implications well into adulthood.”

https://www.cidrap.umn.edu/covid-19/study-links-long-covid-kids-worse-grades-attention-and-social-life

#LongCovid #PublicHealth #CovidisNotOver #WearAMask #GetVaccinated

I dont understand neurotypicality I guess.

A tornado throwing shit at me at 100mph? Whatever.

UNSEEABLE BRAIN INJURING VIRUS PASSED ALONG AIRBORNE??

How is that not scarier?

Just asking.

#COVIDIsNotOver