RhyothemisNov 18

Genetics may influence the effects of vitamin E on cancer risk [news article, 2019]
https://ecancer.org/en/news/15262-genetics-may-influence-the-effects-of-vitamin-e-on-cancer-risk

' "Observational studies of people taking vitamin E have reported benefits, and studies in animal models have suggested a protective effect, but when vitamin E supplements were brought into placebo-controlled clinical trials, the results were null," said Kathryn Hall, PhD, MPH, from the Division of Preventive Medicine at the Brigham.

"This made it easy to assume that vitamin E just doesn't work. But what we've found is that it may have been protective in some and not in others, and that genetic variation is linked to these outcomes." '

#VitaminE #COMT #cancer #genesXenvironment

Genetics may influence the effects of vitamin E on cancer risk

Almost half of all Americans take a vitamin supplement, and yet many large-scale, placebo-controlled clinical trials of various supplements have found little

ecancer
Show threadRhyothemisOct 4

another interesting vitamin E article:

COMT and Alpha-Tocopherol Effects in Cancer Prevention: Gene-Supplement Interactions in Two Randomized Clinical Trials [2019]
https://academic.oup.com/jnci/article/111/7/684/5260812

#vitaminE #cancer #supplements #COMT

COMT and Alpha-Tocopherol Effects in Cancer Prevention: Gene-Supplement Interactions in Two Randomized Clinical Trials

AbstractBackground. Vitamins are among the most frequently used supplements (48% of US adults). However, little is known about contributions of genetic variatio

OUP Academic
RhyothemisDec 31, 2023

"After analyzing data based on the NHANES database from 2013–2018, the results showed that vitamin E intake among U.S. adults was well below the recommended levels and that higher vitamin E intake was negatively associated with COPD incidence."

Association of Dietary intake of vitamin E with chronic obstructive pulmonary disease events in US adults: A cross-sectional study of NHANES 2013–2018 https://doi.org/10.3389/fnut.2023.1124648

See also:
COMT and Alpha-Tocopherol Effects in Cancer Prevention: Gene-Supplement Interactions in Two Randomized Clinical Trials
https://doi.org/10.1093/jnci/djy204

Randomised vitamin E supplementation and risk of chronic lung disease in the Women's Health Study
https://doi.org/10.1136/thx.2010.155028

~

Almonds are a good dietary source of vitamin E. Sunflower seeds have even more per gram or calorie, but can cause acne breakouts in some.

#COPD #vitaminE #cancer #COMT

Association of Dietary intake of vitamin E with chronic obstructive pulmonary disease events in US adults: A cross-sectional study of NHANES 2013–2018

IntroductionSeveral studies have demonstrated that vitamin E intake is negatively associated with the development of several diseases, but the relationship between vitamin E intake and COPD in different groups of people is not clear. The aim was to investigate the relationship between vitamin E intake and COPD in different groups of people.MethodsThis study used data from NHANES (National Health and Nutrition Examination Survey) from 2013–2018. A final total of 4,706 participants were included, univariate versus multivariate logistic regression and restricted cubic spline models adjusted for confounders were used to explore the relationship between vitamin E intake and COPD, and subgroup analyses were conducted to assess whether there are differences in the relationship between vitamin E intake and COPD in different populations or conditions.ResultsAfter adjusting for potential confounders, higher vitamin E intake showed a significant negative association with COPD [Model 1(unadjusted covariates, OR = 0.48;95% CI:0.33–0.70; p < 0.001), Model 2(adjusted for age, sex, and race, OR = 0.48;95% CI:0.31–0.73; p < 0.01), and Model 3(adjusted for all covariates, OR = 0.57;95% CI:0.36–0.91; p = 0.02)]. And a restricted cubic spline curve showed a significant negative correlation between vitamin E intake and COPD (p for nonlinear = 0.2036). In the subgroup analysis, we found a negative association between vitamin E intake and COPD in all subgroups as well.ConclusionAfter analyzing d...

Frontiers
Bud TalbotJul 12, 2023
In case you've ever wondered what an "office" looks like on a #wildfire, here are 2 examples, at least for a #COMT (incident communications technician). One is in the #communications yurt, the other in the front seat of a truck. Both are functional.
Bud TalbotJul 9, 2023

A clean repeater site is a safe repeater site. This one was not safe when we deployed it with fire below. Luckily this mod from Black Hills helped us brush it out. Now it's safe.

#Wildfire #ChrisMountainFire #wildlandfire #COMT #communications

Bud TalbotJul 9, 2023

Best job on the fire

#ChrisMountainFire #wildfire #wildlandfire #COMT #communications

Bud_TJan 29, 2023

Has anyone in my feed ever taken the Associate Level Certified Electronic Technician (CET) exam? I'm wondering if preparing for this cert would help me with my #COMT work in #wildfire.

#CET