CellBioNewsJul 27, 2023

Unraveling a #protein that may inspire a new #biotechnology tool.

#Argonaute #RNA_interference #prokaryotes

https://phys.org/news/2023-07-unraveling-protein-biotechnology-tool.html

Unraveling a protein that may inspire a new biotechnology tool

Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool.

Phys.org
The EMBO JournalApr 21, 2023

A small RNA system ensures accurate homologous pairing & unpaired silencing of #meiotic #chromosomes in C. #elegans

Hiroaki Tabara et al show #argonaute proteins CSR-1 and CSR-2 targeting repeat-derived #lncRNAs to mediate both #synaptonemal complex formation and condensation of unpaired chromosomes

https://www.embopress.org/doi/10.15252/embj.2020105002

Vivek MutalikMar 10, 2023

Long-B prokaryotic #Argonaute systems employ various effectors to confer immunity via abortive infection | bioRxiv

https://www.biorxiv.org/content/10.1101/2023.03.09.531850v1

CellBioNewsFeb 7, 2023

#Argonaute #protein slicing, retention of #RNA fragments plays role in chemical modification of #DNA for #gene silencing.

#viruses

https://phys.org/news/2023-02-argonaute-protein-slicing-retention-rna.html

Argonaute protein slicing, retention of RNA fragments plays role in chemical modification of DNA for gene silencing

Researchers at Indiana University Bloomington have uncovered previously hidden steps of a gene silencing process used to combat viruses and other would-be genome invaders.

Phys.org
lucksmithNov 7, 2022
mandatory factoid for all you #Argonaute fans! cool work reveals the Argonauta egg case is *not* evolutionarily related to the Nautilus shell, and not to other "true shells" in general...it's a novel convergent innovation! via @[email protected] https://www.nytimes.com/2022/11/05/science/octopus-shell-argonaut.html?smid=nytcore-ios-share&referringSource=articleShare