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77 Posts

How many professional programmers are working on pointless and/or actively harmful products?

Give me your best guess.

(If you vote, please boost to diversify the results. It’s polite.)

0–25%
6.3%
25–50%
24.9%
50–75%
48.4%
75–100%
20.4%
Poll ended at .

US HUPO : Bridging ‘Omics to Function | 9-13 Mar, 2024 | Portland, USA --- https://www.ushupoconference.org/#Home-Top

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#proteomics #prot-conf

US HUPO 2024 Conference

Is this the way open science is performed nowadays?

Ten days before official publication of MASST+ in @naturebiotech but presumably after acceptance, all relevant source code was removed from its GitHub repository. It is now a shell repo that only includes a README and data files used for testing. Also no deposition of the code to @zenodo_org, so what's to prevent this history from disappearing as well?

Rather shocking.

Paper: https://www.nature.com/articles/s41587-023-01985-4
Repository: https://github.com/mohimanilab/MASSTplus

Fast mass spectrometry search and clustering of untargeted metabolomics data - Nature Biotechnology

MASST+ speeds up querying of metabolomics mass spectrometry data by two orders of magnitude.

Nature

Weights for the non-enzymatic version of Casanovo v4.x are now available. Use this to analyze data that was generated using a different protease than trypsin, for immunopeptidomics, ...

You can find the model weights on GitHub under the "Assets" of release v4.0.0: https://github.com/Noble-Lab/casanovo/releases/tag/v4.0.0

Note that by default Casanovo will automatically download the tryptic model weights. To use the non-enzymatic model, download the weights file manually and specify it using the `--model` command-line argument.

Release Casanovo v4.0.0 · Noble-Lab/casanovo

4.0.0 - 2023-12-22 Added Checkpoints include model parameters, allowing for mismatches with the provided configuration file. accelerator parameter controls the accelerator (CPU, GPU, etc) that is ...

GitHub

Anyone out there that has time and skills to help me with designing a sticker for the rpx #rstats #bioconductor   package

http://lgatto.github.io/rpx/

It could be based/adapted from @wfondrie 's python ppx package (https://ppx.readthedocs.io/en/stable/) - both packages offer similar functionalities.

R Interface to the ProteomeXchange Repository

The rpx package implements an interface to proteomics data submitted to the ProteomeXchange consortium.

@proteomicsnews blog post | John Yates is speaking in Bethesda tomorrow (9/11/23!) | https://proteomicsnews.blogspot.com/2023/09/john-yates-is-speaking-in-bethesda.html #proteomics
John Yates is speaking in Bethesda tomorrow (9/11/23!)

  Details here! Also -- new lightning talks for the discussion group start in October (great idea!)  I knew this was happening, for real. I ...

Do you wear a watch?

Please boost to make the sample larger.

No. I use my phone.
45.4%
Sure an Apple/other smart watch
30%
A regular, digital watch
3.1%
A regular, analog watch (with hands)
21.5%
Poll ended at .

@austinkocher It really is gorgeous!

One fond memory from living nearby was all of the wonderful music we could hear just walking around rhe neighborhood in the spring time. Talented musicians practicing with their windows open was quite pleasant.

The Peabody Library in Baltimore, Maryland, is one of the most beautiful interior spaces I've ever seen. Worth the visit! #baltimore #architecture #library #maryland #books
@neely obviously some woodworking right?