| SBGrid Consortium | https://sbgrid.org/ |
| BioGrids | https://biogrids.org// |
| SBGrid Data Bank | https://data.sbgrid.org/ |
| Sliz Lab | https://www.slizlab.org/ |
Member News: Congratulations to Stephen Blacklow, Chair and Gustavus Adolphus Pfeiffer Professor of BCMP, and Johannes Walter, Edward S. Wood Professor of BCMP at Harvard Medical School on their election to the National Academy of Sciences!
More here: https://www.nasonline.org/news/2026-nas-election/
Community Announcement: Upcoming event from our partners at Instruc-ERIC
Instruct-ERIC Webinar Series: Structure Meets Function 47
Tuesday, May 19, 2026
*Casper Berger from Rosalind Franklin Institute on Adaptive Milling: imaging feedback-driven automated lamella fabrication for in situ structural biology
*Chiara Marabelli from Università di Pavia on Establishing a Vitrification Protocol of Large Ventricular Cells from Murine Models for Volume Imaging
Register here: https://instruct-eric.org/events/structure-meets-function-47/
New Title Alert: af_analysis- is a Python package for analysis of AlphaFold protein structure predictions from AlphaFold 2/3, ColabFold, AlphaFold-Multimer, AlphaPulldown, Boltz1, Chai-1, and MassiveFold.
Learn more here: https://github.com/samuelmurail/af_analysis/
Community Announcement:
Upcoming event from our partners at Instruc-ERIC
Calorimetric and Spectroscopic Characterization of Biomolecules
September 7-11, 2026 | CEITEC Brno, Czech Republic
Organized in collaboration with the Biomolecular Interactions and Crystallography Core Facility at The Central European Institute of Technology
Register here: https://instruct-eric.org/events/instruct-course-on-calorimetric-and-spectroscopic-characterization-of-biomolecules
Meharry Medical College student Mudiare Ikoba highlights a publication in the Journal of Cell Biology from SBGrid member Antonina Roll-Mecak and colleagues in which the authors analyze the structure of the RPGR-TTLL5 complex to shed light on the pathomechanism of retititis pigmentosa.
Read more here: https://medium.com/sbgrid-community-news/how-proteins-work-together-to-support-our-vision-e4e1a30a6850
New Title Alert: AF3Complex- is a model equipped with the same improvements as AF2Complex, along with a novel method for excluding ligands, built on AlphaFold 3.
Learn more here: https://github.com/Jfeldman34/AF3Complex
Fisk University student Cariuna Ellison's highlight features an eLife publication from Jochen Zimmer's group at University of Virginia School of Medicine that describes the use of Cryo-EM to reveal how CvHAS utilizes a two-step mechanism to navigate the balance between substrate specificity and degeneracy.
Read more here: https://medium.com/sbgrid-community-news/molecular-proofreading-mechanisms-of-enzyme-binding-567ed3b5c4f2
If you missed our March webinar with José Luis Vilas Prieto on Image processing made simple with ScipionTomo, you can catch up with the recorded version on YouTube.
More here: https://youtu.be/uE8ej9ZO-M8
New Title Alert: PXDesignBench- is a protein design evaluation suite for monomer and binder tasks that standardizes sequence generation, structure consistency assessment, and downstream metrics across tools including ProteinMPNN, ESMFold, AlphaFold2, and Protenix.
Learn more here: https://github.com/bytedance/PXDesignBench
New Title Alert: MolDiff- is a diffusion framework designed for generating 3D drug-like molecules, achieving a sampling success rate of over 99%. This tool addresses the atom-bond inconsistency problem in 3D molecule diffusion generation and serves as a backbone for applications such as pocket-based generation and linker generation.
Learn more here: https://github.com/pengxingang/MolDiff/
