SBGrid's eLife paper received a citation in April from Dirk Slotboom from University of Groningen in Nature Communications: Shared structural mechanisms of alternating access between the secondary peptide transporter SbmA and ABC transporters.
Shared structural mechanisms of alternating access between the secondary peptide transporter SbmA and ABC transporters - Nature Communications
SbmA is a proton-driven transporter that imports antimicrobial peptides andstructurally resembles the transmembrane domain of ABC-transporters. Here, authors show through cryo-EM structures, EPR spectroscopy, and MD simulations that SbmA undergoes ABC-transporter-like conformational changes consistent with an alternating-access transport mechanism.
