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Professor at University of Freiburg; Associate Editor at RSC Chemical Science; Chemical Biology, Phosphatase Biology
websitehttps://www.bioss.uni-freiburg.de/groups/intergrative-signalling-studies/home/

Three articles published yesterday in #Science, Science Advances & Nature 🤔

Women remain underrepresented among faculty in nearly all academic fields https://www.science.org/doi/10.1126/sciadv.adi2205

Toxic workplaces are the main reason women leave academic jobs https://www.nature.com/articles/d41586-023-03251-8

Women faculty feel ‘pushed’ from academia by poor workplace climate
https://www.science.org/content/article/women-faculty-feel-pushed-academia-poor-workplace-climate

The Chemical Biology & Physiology 2023 Conference in Portland, Oregon is fast approaching! The meeting will be held from the 14 - 17 December and you have until the 30th of October if you'd like to submit a poster abstract.

Find out more at: http://bit.ly/46J0h0f

#Chemistry #Conference

Chemical Biology and Physiology 2023 | OHSU

Chemical Biology and Physiology Conference 2023, December 14-17, 2023

Online now! A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00242-8?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Interested in developing Chem Biol methods to discover the role of tubulin PTMs in immune cells in a collab project (@SNSF Sinergia) between us & Aumeier (@unige), Sixt (ISTA), Stein (@unifr) labs? If so, let us know! PhD and Postdoc positions available: https://www.epfl.ch/labs/lcbm/immunet/
List of all MDPI predatory journals

MDPI as a publisher of open-access scientific journals was spun off from the Molecular Diversity Preservation International organization. It was formally registered by Shu-Kun Lin and Dietrich Rordorf in May 2010 with it...

Predatory Reports

Nature's nutcracker can crush pesticide residue

Highly non-degradable chemicals such as PFAS and pesticides can have useful properties in some situations, but are be extremely difficult for nature to remove afterwards.

Inside E. coli bacteria, Ditlev Brodersen's (and Jan Enghild's) groups have now found an enzyme, C-P lyase, that enables the microbe to degrade highly stable chemicals.

Read more about the results in Nature Communications: https://mbg.au.dk/en/news-and-events/news-item/artikel/natures-nutcracker-can-crush-pesticide-residue

Nature's nutcracker can crush pesticide residue

Highly non-degradable chemicals such as PFAS and pesticides can have useful properties in some situations, but are be extremely difficult for nature to remove afterwards. Now researchers from Aarhus University have found that certain bacteria use an enzyme that acts as a molecular nutcracker to crush the harmful substances.

Mass spectrometry analysis of phosphotyrosine‐containing proteins | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/mas.21836?af=R #proteomics

Happy to share our latest #PhosTAC paper where we target #Tau for dephosphorylation. #chemicalbiology #heterobifunctional

https://pubs.acs.org/doi/10.1021/jacs.2c11706

Be cautious when using lipidation together with polybasic sequences to guide your bioactive peptides to cellular compartments: We found that lipidation causes induction of MAPK signaling and calcium release irrespective of the original bioactivity and peptide sequence: https://onlinelibrary.wiley.com/doi/10.1002/psc.3469
JOB ALERT: Postdoctoral Researcher in Organic Chemistry or Chemical Biology. The research lab of André Nadler @nadlerlab @mpicbg is seeking a talented, curiosity-driven postdoctoral scientist to pursue projects investigating the transport of chemically modified lipid probes in liver and intestinal organ models (organoids). https://www.mpi-cbg.de/join-us/open-positions/job-offer/postdoctoral-researcher-in-organic-chemistry-or-chemical-biology #mpicbg #postdocjob
Postdoctoral Researcher in Organic Chemistry or Chemical Biology

The lab of André Nadler is seeking a talented, curiosity-driven postdoctoral scientist to pursue projects investigating the transport of chemically modified lipid probes in liver and intestinal organ models (organoids). Applications will be assessed on a rolling basis.

MPI-CBG