Cell Chemical Biology

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Cell Chemical Biology is a #chemicalbiology journal from @cellpress.
Online now! Mechanism by which a linoleic acid metabolite suppresses cancer cell growth by inhibiting mTOR https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00137-6?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Online now! The cytotoxic effect of prexasertib is a consequence of dual inhibition on both CHK1 and AMPK https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00112-1?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Online now! Identification of an STING inhibitor targeting the allosteric transmembrane domains https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00110-8?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Online now! Redox regulation of neuroinflammatory pathways contributes to damage in Alzheimer’s disease brain https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00109-1?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Online now! NEK7 Cys298 is important for NLRP3 inflammasome and targetable by dimethyl fumarate https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00108-X?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Online now! CryoSeek identification of glycofibrils with diverse compositions and structural assemblies https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00078-4?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Structural insights into inhibition mechanism of the helicase-primase complex from human herpesvirus 1 https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00076-0?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Genetically encoded manipulation of ATP/ADP ratio in human cells uncovers proteomic and physiological signatures of energy stress https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00074-7?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #chembiol
Assessing the suitability of deubiquitylases as substrates for targeted protein degradation https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00100-5?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(26)00075-9?rss=yes&utm_source=dlvr.it&utm_medium=mastodon