Happy to share our latest #PhosTAC paper where we target #Tau for dephosphorylation. #chemicalbiology #heterobifunctional
https://pubs.acs.org/doi/10.1021/jacs.2c11706
Inspired by PROTACs, new degraders are emerging that harness endocytosis and autophagy to send a wide array of targets to the lysosome for destruction.