Happy to share our latest #PhosTAC paper where we target #Tau for dephosphorylation. #chemicalbiology #heterobifunctional

https://pubs.acs.org/doi/10.1021/jacs.2c11706

Happy #Heterobifunctional Holidays from the Crewslab! #PROTAC #chemicalbiology #Yale
The lysosomal degraders - Nature Biotechnology

Inspired by PROTACs, new degraders are emerging that harness endocytosis and autophagy to send a wide array of targets to the lysosome for destruction.

Nature