Dagmar Iber

84 Followers
100 Following
53 Posts
President of the ETH University Assembly & Professor for Computational Biology: data-driven modeling & simulation of emerging phenomena in development & disease
Websitehttps://bsse.ethz.ch/cobi
InstitutionETH Zurich
SNSF award for Roman Vetter's research video

RT @KristinBvS
«…ces économies sont une erreur dans une période de crise où l’on devrait (…) investir dans notre bien le plus précieux, la connaissance et l’innovation». ⁦@MartinVetterli⁩ ⁦@Joel_Mesot⁩ ⁦@EPFL⁩ ⁦@ETH⁩ ⁦@Conseil_EPF⁩ https://www.24heures.ch/la-suisse-a-besoin-dune-task-force-scientifique-permanente-436403010993
Paroles de présidents d’EPF: «La Suisse a besoin d’une task force scientifique permanente»

Martin Vetterli et Joël Mesot, présidents des deux écoles polytechniques fédérales dont la parole commune est rare, évoquent les principaux défis auxquels ils sont confrontés.

Tamedia Publications romandes S.A.

RT @scietyHQ
Looking for an overview of the main findings of the #ReviewedPreprint below? Then check out this Twitter thread by corresponding author @DagmarIber 👇

https://twitter.com/DagmarIber/status/1489479705292156933. https://twitter.com/scietyHQ/status/1650425596516737024

Dagmar Iber on Twitter

“How does #cell size affect #patterning precision in the #embryo? A novel cell-based simulation framework reveals the impact of cell diameter on #morphogen gradient variability in #tissue #development. Check out our latest pre-print: https://t.co/WEY9nUi9Nf 🧵 (1/6)”

Twitter
RT @theChaudhurilab
New preprint alert! 🚨 Excited to share @DhirajIndana’s phenomenal work on the mechanism of lumen formation in a human epiblast model. A short thread 🧵https://www.biorxiv.org/content/10.1101/2023.04.20.537711v1

Congratulations to Roman Vetter from our group for winning an award in the @snf_ch #image #competition with one of his stunning videos of tissue growth:

https://www.flickr.com/photos/snsf_image_competition/52797439078/in/album-72177720307288892/

#SwissScienceVideo

Stay tuned for his paper!!

"Tumour growth simulation" by Roman Vetter, ETH Zurich

Flickr

RT @scietyHQ
How morphogen gradients yield precise patterning is an important question in #DevelopmentalBiology. New study investigates the impact of cell size in this context.

#ReviewedPreprint from the @DagmarIber lab @ETH_BSSE, evaluated @ReviewCommons.

https://sciety.org/articles/activity/10.1101/2022.02.02.478800?utm_medium=social&utm_campaign=sci_tweets_2023

Impact of cell size on morphogen gradient precision

Tissue patterning during embryonic development is remarkably precise. We numerically determine the impact of the cell diameter, gradient length, and the morphogen source on the variability of morphogen gradients and show that the positional error increases with the gradient length relative to the size of the morphogen source, and with the square root of the cell diameter and the readout position. We provide theoretical explanations for these relationships, and show that they enable high patterning precision over developmental time for readouts that scale with expanding tissue domains, as observed in the Drosophila wing disc. Our analysis suggests that epithelial tissues generally achieve higher patterning precision with small cross-sectional cell areas. An extensive survey of measured apical cell areas shows that they are indeed small in developing tissues that are patterned by morphogen gradients. Enhanced precision may thus have led to the emergence of pseudostratification in epithelia, a phenomenon for which the evolutionary benefit had so far remained elusive.

Sciety

Not only @ETH & @EPFL get hit hard with exploding student numbers, 🇨🇭federal budget woes, and limited access to 🇪🇺 @ERC_Research grants & networks.

@NZZ interview with Uni Zurich rector Michael Schaepman @UZH_ch:

https://magazin.nzz.ch/nzz-am-sonntag/schweiz/warum-zuerich-eine-zweite-uni-brauchen-koennte-ld.1733580

RT @EbisuyaMiki
W/ the spirit of St Jordi🐉, I read my favorite book (only 3 chaps, though).
"Scaling: Why is Animal Size so Important?" taught me animal size dictates many parameters, including time. Rather than real clock time, using physiological time helps understand animals comprehensively
RT @ClotildeCadart
Our paper is out! Xenopus embryos follow #kleiber’s power law between metabolic rate and body mass. But triploids embryos which are made of fewer larger cells have a lower metabolic rate than diploids. 1/3

We are looking for a #PhD student to extend our 3D cell-based #tissue #simulation framework:

https://twitter.com/DagmarIber/status/1641347393630224384

Not done with your #Master yet? Do your thesis with us & stay for a PhD:

https://twitter.com/DagmarIber/status/1628075320208228352

Come & join us @ETH @ETH_BSSE: https://jobs.ethz.ch/job/view/JOPG_ethz_X8X7dZDPDuq9Qy57Xd
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RT @DagmarIber
We have 2 #Master #thesis opportunities in our…
https://twitter.com/DagmarIber/status/1628075320208228352

Dagmar Iber on Twitter

“Excited to introduce #SimuCell3D, an #opensource 3D cell-based model to simulate large and complex tissues at high resolution. Check out our latest @biorxivpreprint https://t.co/ZA13Wsvd0g A short summary thread about the software tool:🧵(1/9)”

Twitter