Assistant Professor at University of Colorado School of Medicine. Our lab studies protein homeostasis and turnover using proteomics, bioinformatics & iPSC. Previously Stanford CVI. #TeamMassSpec
We are hiring graduate students and post-doctoral fellows! Visit our website at https://laulab.net and follow us on @edwardlau and on https://post.news/edwardlau!
Wow, this seems a very draconian and impractical stance for #NIH to take for its grants involving foreign partners! 👇
Article below haa a full takedown. #academicchatter #funding @academicchatter
"Beginning October 1, 2023, foreign subaward recipients will be required to provide the U.S. prime grantee “copies of all lab notebooks, all data and all documentation that support the research outcomes…no less than every six months, or more frequently based on risks”"
Seems sensible to me right now, but with the speed of change, how long will this hold true? What properties or abilities would you expect an AI to have for it to qualify for authorship in a scholarly context?
Personal responsibility, consent and agency come to mind, but I have no idea how one would validate these properties.
I suspect scientific editors will be confronting this soon. 2/
Enhancement of a prime editing system via optimal recruitment of the pioneer transcription factor P65 https://www.nature.com/articles/s41467-023-35919-0
🐦🔗: https://twitter.com/ChemistryNews/status/1615336654264492038
Prime editing represents a great advance to the genome editing field but is currently limited by the editing efficiency. Here the authors look to improve the efficiency by recruiting target proteins and show that the transcription factor P65 could enhance the desired editing outcomes at different gene loci.
dplyr 1.1.0 is out now! 🎉
This is a huge release, so we split the announcement into 4 posts to be released throughout the week. #rstats
Today we'll focus on joins, including:
- join_by()
- Inequality and rolling joins
- Two new quality control arguments
We have integrated semi-supervised PSM rescoring in the ANN-SoLo open modification spectral library search engine.
Open modification searching = identify modified peptides without explicitly having to specify PTMs.
PSM rescoring = more accurate and sensitive spectrum identification results.
Open modification searching + PSM rescoring = Win! 💪
Now published in JPR: https://pubs.acs.org/doi/10.1021/acs.jproteome.2c00616
Try ANN-SoLo: https://github.com/bittremieux/ANN-SoLo
Gabriele Pollara
Ron Beavis ❌
Andrew L. Hufton
David R. Liu
Davis Vaughan
Wout Bittremieux