Welcome to our first-year Integrated Physiology students on campus!
It was a pleasure having summer students Abigiya Abate and Gabe Wu work with us in the lab. Both did a stellar job and will be an asset to any graduate programs!
Fun conference at @us_hupo last week. Congrats again to Jordan who received the HUPO Travel Award and gave an excellent oral presentation on his project!
Excited for @us_hupo conference next week. Come check out the talk by Jordan Currie (OA07.01) on protein turnover and localization analysis in Parallel Session 07: Protein Dynamics and Turnover on Tuesday 3/7 11:30-12:50!
Congrats to Jordan Currie, who won our local "3 Minute Talk" competition discussing his project on spatiotemporal proteomics, and will be invited to compete in the regional round 🎉
Share your work on how aging affects the cardiovascular system! Check out the AJP special issue on the Impact of Aging on the Cardiovascular System for details:
http://ow.ly/T35E50Lt7B8
Impact of Aging on the Cardiovascular System
<p>The <em>American Journal of Physiology-Heart and Circulatory Physiology</em> publishes original investigations on the physiology of the heart, blood vessels, and lymphatics, including experimental and theoretical studies of cardiovascular function at all levels of organization ranging from the intact animal to the cellular, subcellular, and molecular levels. It embraces new descriptions of these functions and of their control systems, as well as their bases in biochemistry, biophysics, genetics, and cell biology. Preference is given to research that provides significant new insights into the mechanisms that determine the performance of the normal and abnormal heart and circulation.</p>
American Journal of Physiology-Heart and Circulatory PhysiologyA new HUPOST our lab co-wrote with @
[email protected] where we discussed recent work on measuring protein turnover in intact animals
https://hupo.org/News/13001621Congrats to Veronica for passing the BSBT exam! You did a great job!
Prior selection of mRNA features not only improved protein predictions, but may also help find new protein-level driver genes. E.g., using a directed graph model, we predict that the LACTB mRNA may have an outsized effect on mitochondrial ribosome protein abundance.
The data suggests degradation of supernumerary interactors is a driver of protein levels. While this was known for large complexes, this phenomenon is widespread and affects many small stable complexes incl. propionyl-CoA carboxylase, mito. calcium uniporter, calcineurin, etc.