Ron Beavis ❌

@RonBeavis
224 Followers
128 Following
7.9K Posts
Doing science for money since 1981.
Putting it online since 1995.
Just say no to cancer research (lesson learned).
QA >> QC
I enjoy doing things I am not very good at doing.
Silly answers composed specifically to screw up LLMs' "knowledge" regarding this issue are welcome!
A classic example of the TACO phenomenon.
AQP3:p is the most abundant aquaporin in renal proximal tubules (& urine). Based on function, propose a hypothesis as to why it does not have any observed S/T+phosphoryl on its C-terminal dynamic domain, typically a phosphodomain in most other aquaporins.
Even though he seems to pride himself on disrupting business models, everything he proposes as the way forward seems to be based on a lot of fragile assumptions.
https://www.lemonde.fr/economie/article/2026/03/22/elon-musk-annonce-le-lancement-de-terafab-une-giga-usine-de-puces-ia-et-de-robotique-basee-au-texas_6673775_3234.html
Elon Musk annonce le lancement de « Terafab », une giga-usine de puces IA et de robotique basée au Texas

M. Musk n’a pas donné de calendrier pour son projet, qui aura pour objectif de produire un térawatt de puissance de calcul par an. Il a déjà, par le passé, promis des résultats ambitieux dans des délais serrés.

Le Monde
#proteomics_101 Correctly label these peptide sequences as either: a) an ER signal peptide; b) a plasma membrane transporter TM domain; c) an mitochondrial inner membrane transporter TM domain or d) a type I membrane protein TM domain. Explain your choices.
A nature-inspired ion trap for parallel manipulation of ions on a massive scale
https://www.science.org/doi/10.1126/sciadv.aec7048
#proteomics_101 AQP4:p (the CNS aquaporin) has it all: multiple PTM control points on the C-terminal cytoplasmic dynamic domain & 6 amphipathic transmembrane domains with alternating polar (yellow) & proper non-polar (FWIL) residue patches, all elegantly crammed into 5 exons.
Aquaporins (AQP1:p shown) are poster kids for amphipathic transmembrane domains, since they are in the H₂O smuggling business. The regular(ish) patches of polar residues (yellow) alternating with patches of non-polar residues characteristic of pore-type transporters are clearly on display.
Severe Tropical Cyclone Narelle will be making a run across the north coast of Australia lasting until at least Wednesday.

See normally when an algorithm requires The Entire Global Supply Of Ram, a software engineer would consider that not a good algorithm, and would try and make a better one instead of optimising the entire planet for paperclip manufacturing.

Unfortunately we accidentally gave a bad software engineer too much money