D Flemming Hansen

22 Followers
28 Following
10 Posts

Our recent research in PNAS 👇 reveals the dynamic world of enzymes like never before!

We used NMR spectroscopy and CPMG relaxations to unveil hidden conformations, connecting them to enzymatic activity and inhibitor potency. Likely important for drug design! #NMR #Enzymes #PNAS

https://doi.org/10.1073/pnas.2310910120

As requested by Reid Alderson, ChemEx is now in #NMROnline!

We would like to thank D. Flemming Hansen (@dflemminghansen) for providing the data, and Guillaume Bouvignies for his support with the ChemEx integration.

@bioinformatics @biophysics @chemistry @compchem @nmrchat @physics @strucbio

#biochemistry #bioinformatics #biology #biophysics #chemistry #CompChem #metabolomics #NMR #NMRChat #physics #SoftwareDevelopment #SoftwareEngineering #StructuralBiology #WebDev

Thank you, D. Flemming Hansen (@dflemminghansen) and Prof. Lewis E. Kay + Kay Lab for providing data for testing.

Merci beaucoup, Guillaume Bouvignies for your help and support with the integration of ChemEx into #NMROnline.

@bioinformatics @biophysics @chemistry @compchem @nmrchat @physics @strucbio

#biochemistry #bioinformatics #biology #biophysics #chemistry #CompChem #metabolomics #NMR #NMRChat #physics #SoftwareDevelopment #SoftwareEngineering #StructuralBiology #WebDev

1.2 GHz NMR in Lille, which is part of Infranalytics infrastructure: a video with English subtitles presenting the project is available via the link below:

https://youtu.be/bIiSrPk_l2E

Le CNRS et l’Université de Lille accueillent le Spectromètre RMN 1200 MHz

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Upcoming (part 6, new)
Barcelona March 20-21 http://www.ccit.ub.edu/bir/
EPR 2023 Paris May 22-26 https://epr2023.sciencesconf.org
Adriatic June 1-4 https://adriatic-nmr-conference.hkd.hr
Metabolomics June 18-22 https://metabolomics2023.org
Zakopane June 18-24 https://school.web.amu.edu.pl
EAS November 13-15 https://eas.org
BIR, Barcelona Integrative Resonance symposium

Barcelona Integrative Resonance symposium

Open position Research Technician in protein production, biochemistry and wetlab management.

Join our dynamic international team to work on fascinating biological questions, such as mitochondrial import and allostery, develop new isotope-labeling schemes, and NMR spectroscopy. Please forward

The position become a non-limited position.
Get insights into the scientific environment at ista.ac.at and
on the youtube channel, such as https://www.youtube.com/watch?v=WLuS5nGOkw8

Apply here: https://ist.ac.at/en/job/research-technician-lab-management-research-group-schanda/

Work and Research at the Institute of Science and Technology Austria (ISTA)

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Many thanks to UCL President & Provost Dr Michael Spence for visiting our department / institute today.

Amazing visit with excellent questions and very enjoyable to talk about about #AI and #NMR as well as scopes for 'NMR for the masses'.

Yesterday, we launched #NMRD – ALPHA, a successor to NMR Draw, but the results don't stop there!

We're building #NMROnline at the same time, with our current focus being the integration of ChemEx and NmrPipe.

@bioinformatics @biophysics @chemistry @compchem @massspec @nmrchat @physics @strucbio

#biochemistry #bioinformatics #biology #biophysics #chemistry #CompChem #MassSpec #metabolomics #NMR #NMRChat #physics #spectroscopy #StructuralBiology

@SjorsScheres The short answer is 'yes'. Backbone #NMR chemical shifts mostly reflect secondary structure, which is not very different between #tau #amyloid strains. Long range distances from either #NMR or #EPR would clearly help.