Alberto Ciccia

@aciccia
32 Followers
46 Following
9 Posts
Scientist at Columbia University interested in #DNADamage #DNARepair #GenomeStability #GenomeEditing #CRISPR
lab websitehttps://www.ciccialab.com
webpagehttps://www.genetics.cuimc.columbia.edu/profile/alberto-ciccia-phd
twitter@CicciaAlberto
Alberto CicciaDec 23, 2022

Exciting to see that the base editing strategies for gene inactivation that Pierre Billon in our lab and the Adli lab contributed to develop have been useful to engineer T cells for the treatment of a patient with T-ALL! #iSTOP #CRISPRSTOP #GenomeEditing #CRISPR #cancer

World-first use of base-edited cells to treat ‘incurable’ leukaemia
https://www.ukri.org/news/world-first-use-of-base-edited-cells-to-treat-incurable-leukaemia/#:~:text=A%20patient%20with%20'incurable'%20T,acute%20lymphoblastic%20leukaemia%20in%202021

Base-edited CAR T cells for combinational therapy against T cell malignancies
https://www.nature.com/articles/s41375-021-01282-6

World-first use of base-edited cells to treat ‘incurable’ leukaemia

A patient with ‘incurable’ T-cell leukaemia has been treated with base-edited T-cells in the world’s first reported use of a base-edited therapy.

Alberto CicciaDec 20, 2022

For more information, see below

http://www.ciccialab.com
#DNADamage #DNARepair #GenomeEditing #CRISPR

Alberto CicciaDec 20, 2022
We have open postdoctoral positions to study the DNA damage response at nucleotide resolution using base editing screens or develop new precision genome editing applications. Come and join us! http://www.ciccialab.com
#DNADamage #DNARepair #GenomeEditing #CRISPR
Alberto Ciccia laboratory

Alberto Ciccia laboratory, Department of Genetics and Development, Columbia University Medical Center

ciccialab