Mastodawn

Kristoffer H. Johansen Jan 25, 2023

I am thrilled to announce that @[email protected] has granted us a 150k€ from an #ERCPoC to develop new #allergy vaccines. Congrats to @[email protected] @[email protected] @[email protected] from @[email protected] and the rest of the team. We hope to make allergic patients’s life better soon!

🐦🔗: https://twitter.com/esperdet/status/1617973572605210625

Esperanza Rivera de Torre on Twitter

“I am thrilled to announce that @ERC_Research has granted us a 150k€ from an #ERCPoC to develop new #allergy vaccines. Congrats to @AndreasLaustsen @TimothyPJenkins @KrisHaurum from @DTUtweet and the rest of the team. We hope to make allergic patients’s life better soon!”

Twitter

Kristoffer H. Johansen Jan 11, 2023

RT @[email protected]

Please join us to learn more about the fascinating biology of T-cell antigens and their evolving application in cancer therapeutics in this min-symposia at DTU. We have four excellent speakers providing insight on T-cell antigens from the basics to clinic…https://lnkd.in/dgMAEBUU

🐦🔗: https://twitter.com/sunny0744/status/1612942472396640257

Sunil Kumar Saini on LinkedIn: #dtudk #dtu #tcells #cancer #immunotherapy

Please join us to learn more about the fascinating biology of T-cell antigens and their evolving application in cancer therapeutics in this min-symposia at…

Kristoffer H. Johansen Dec 23, 2022

Kilian Schober Dec 22, 2022

We observed an unexpected rise in #IgG4 #antibodies after repeated #SARS-CoV-2 #mRNA vaccination.

This work is now published at #Science Immunology.
https://www.science.org/doi/10.1126/sciimmunol.ade2798

IgG4 is a non-inflammatory IgG subclass and we see a deterioration in Fc-mediated effector functions like phagocytosis and complement deposition, while Fab-mediated avidity maturation and cross-neutralization are preserved.

What does this mean for protection? We don't know and it's complicated. Read the paper!

Kristoffer H. Johansen Dec 21, 2022

DaveFinlayTCD Dec 21, 2022

RT @DelgoffeLab
Thrilled to kick off the holiday season with a new paper from the lab! Out in @NatImmunol today, we explore an unexpected function of terminally exhausted T cells and their contribution to the immunosuppressive tumor microenvironment. 🧵 1/ https://www.nature.com/articles/s41590-022-01379-9

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity - Nature Immunology

Exhausted CD8+ T cells with diminished effector functions accumulate in tumors. Here, the authors show that hypoxia induces a suppressive phenotype in exhausted T cells and that interfering with hypoxia-mediated CD39 expression limits immunosuppression in the tumor and augments immunotherapy, resulting in arrest of tumor growth.

Nature

Kristoffer H. Johansen Dec 21, 2022

#introduction !

I’m an immunologist from #Denmark, with a PhD from #NIH and #UniversityofCambridge where I used #CRISPR screens to dissect #Tcell integrin activation.

Now I’m a postdoc at #TechnicalUniversityofDenmark (#DTU ). My interest currently revolves around using/developing novel CRISPR tools for T cell editing as well as using CRISPR to identify novel #immunotherapeutic targets.

Also I love my 2 year old son and my wife, and have a passion for sailing and biotech innovation!