Dr Juliet Dukes πŸπŸŸπŸ€πŸΈπŸ”πŸˆπŸ™πŸ¦‚πŸ‘πŸ‚πŸ¦Ÿ

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104 Following
33 Posts

Research Manager for @FRAMEcharity. Zoologist, geneticist, animal advocate.

Views partially formed & may change upon new info.
#Ethics #MS #MultipleSclerosis β“‹

How the nuthatch got its name.
Published in 2016, this brilliant comic by artist Joe Dator somehow feels even more timely in 2023. #art

Do you #supervise #undergraduate or #Masters projects?
Interested in developing non-animal #research methods and #replacement of #animals in #animalresearch?
@FRAMEcharity offers small
#grants for:
πŸ“† 6–10 wks
πŸ’· Β£350 per wk stipend
πŸ”¬ Up to Β£1000 consumables

#3Rs #NAMs #humanescience ⬇️⬇️⬇️

https://frame.org.uk/what-we-do/summer-studentship-programme/

Summer Studentship Award Programme | FRAME

The FRAME Summert Studentship Programme supports undergraduate research projects relating to the development of animal alternative methods.

FRAME

Are you an #undergraduate or #Masters student? Interested in development of non-animal #research methods and #replacement of #animals in #animalresearch?

We offer small #grants forπŸ“† 6–10 weeks
πŸ’· Stipend: Β£350 per week
πŸ”¬Consumables: Up to Β£1000 max

#3Rs #NAMs #humanescience ⬇️⬇️

https://frame.org.uk/what-we-do/summer-studentship-programme/

Summer Studentship Award Programme | FRAME

The FRAME Summert Studentship Programme supports undergraduate research projects relating to the development of animal alternative methods.

FRAME

Many researchers use CO2 as an anaesthetic for bumble bees, but now Anna Cressman and Etya Amsalem have discovered that the gas has side effects, affecting the insects' recovery and also impacts worker and queen bee fertility differently

https://journals.biologists.com/jeb/article/226/1/jeb245431/286613

CO2 bee anaesthetic can cause complications

Most people don't really pay attention to the air they breathe. However, if you go up a mountain, where the oxygen levels are lower, you'll notice as you huff and puff while taking a normal walk around town. Changes in the amounts of the different gases that make up the air we breathe can have noticeable effects in other animals as well, especially insects. β€˜Low concentrations of carbon dioxide (CO2) are often used as an attractant or repellent’, says Anna Cressman of Pennsylvania State University, USA; however, high concentrations can cause behavioural and physiological changes, and can even result in unconsciousness. Frequently, researchers use 100% CO2 to anaesthetize insects (called CO2 narcosis), but the side-effects of exposure to high levels of CO2 are often not considered. Working with Etya Amsalem, also of Pennsylvania State University, Cressman asked what is causing these side-effects in bumblebees (Bombus impatiens) – the lack of oxygen, or the high level of CO2 itself.Carbon dioxide is usually found at levels of around 0.04% in normal air, so the duo pumped either 100% CO2, 50% CO2, normal air with low oxygen, or 100% nitrogen gas (which means that there is no oxygen) into a chamber containing bees for 1 min, recording how many of the bees passed out, and then filmed the insects to monitor how they behaved once they awoke, as well as checking how the different gases affected bees with different roles, queens and workers, in the colony.Sure enough, when the team compared the effects of pure CO2 and 100% nitrogen, the bees’ responses were quite different. Even though both gases knocked the bees out, after recovering from the sedation, the bees that had inhaled 100% CO2 had different side-effects from the bees anaesthetised with pure nitrogen. The CO2-anaesthetised bees pumped their abdomens more and the queens took longer to regain consciousness. In addition, when Cressman compared the effects of the different gases on worker and queen bees, the workers produced smaller eggs after several doses of 100% CO2, whereas the queens produced larger eggs after a single dose of the pure gas. Cressman also compared the impact of the two gases on the expression of six specific genes – involved in egg production and protection from low oxygen levels – and she discovered that the genes reacted differently.The responses of the queen bees and workers to pure CO2 also differed: the queens seemed to be more vulnerable to the gas than the workers, only requiring one dose, to begin showing side-effects during their recovery, in contrast to the workers, which required multiple doses of the gas before the side-effects became apparent. β€˜The fact that the physiological changes are different suggests that CO2 is not simply depriving the bees of oxygen but does something else and is likely to have a more direct impact on cells’, Amsalem concludes.So, inhaling CO2 can affect bees with different roles in the colony in different ways, and researchers should be aware of the potential complications that this may cause when using the gas to anaesthetize insects in their experiments.

The Company of Biologists

Forget #BlueMonday and make today all about the beauty of INSECTS! Let’s spread some joy & share our snaps of #BlueBugs πŸ¦‹

Here’s one of my favourites: a Blue Ground beetle (Carabus intricatus) πŸ’™

We're looking for a Fundraising and Volunteer Coordinator to join our small and supportive team! Want to work for a science-based organisation promoting and fund the #replacement of #animals in #medicalresearch?
We're a #virtualorganisation so this is fully #remoteworking for anyone who can legally work in the #UK.
Have a looksee: πŸ‘‡
#fundraising #team #work #charityjobs #charityjob #science
https://frame.org.uk/latest/were-hiring-fundraising-volunteer-coordinator/
We're hiring: Fundraising & Volunteer Coordinator | FRAME

See what FRAME had to say about We're hiring: Fundraising & Volunteer Coordinator

FRAME

FDA no longer needs to require #animaltests before human drug trials

"In place of the 1938 stipulation that potential drugs be tested for safety and efficacy in animals, the law allows FDA to promote a drug or biologicβ€”a larger molecule such as an antibodyβ€”to human trials after either animal or nonanimal tests."

#AnimalResearch #3Rs #HumaneScience

https://www.science.org/content/article/fda-no-longer-needs-require-animal-tests-human-drug-trials

FDA no longer needs to require animal tests before human drug trials

New law welcomed by animal welfare groups, but others say change won’t happen fast

Simpler times.

Newspaper clipping, 1906.

The bit about a lawyer being stopped from entering a music hall in the US because its facial recognition system picked up that she's part of a law company that's suing them is even crazier than I thought.

The law company isn't suing the music hall - it's suing a restaurant, in another state, which is owned by the hall's parent company MSG Entertainment. MSG gone ahead and harvested photos of all the lawyers in the firm and fed it to an image recognition system to ban them from every MSG Entertainment owned location.

People always tell me that if you've got nothing to hide then you've got nothing to fear. She's got nothing to hide and they still went after her.

If this doesn't start making people worried about facial recognition then there's serious trouble coming.

https://arstechnica.com/tech-policy/2022/12/facial-recognition-flags-girl-scout-mom-as-security-risk-at-rockettes-show/
MSG defends using facial recognition to kick lawyer out of Rockettes show

MSG Entertainment began using facial recognition at venues in 2018.

Ars Technica