Oh FOR FUCK’S SAKE!

Ivermectin doesn’t do shit for hantavirus. I know. I treated multiple cases in residency. Can we stop with the antihelminthic for viruses shit already?!? It was an OK theory, but it hasn’t panned out, and dumb motherfuckers who just can’t seem to live their lives without pissing away their savings on some grifter’s horseshit need to find a better snake oil. Jesus. Fuck.

@mcnado wow, is this dart board method medicine or grift method medicine they keep proposing?
@autolycos @mcnado it's just stupid deep state paranoia.
"They're out to get us and make money, so they won't let us have the good stuff"
@tjbutt58 all the while it's the deep states that keep countries running when the public-facing politics are in scrambles.

@mcnado Horseshit, indeed! Ivermectin: making sure your horses shit healthy poo that's not full of active parasites...

(I know you know this already. I just couldn't resist the connection, after actually giving ivermectin to horses and dealing with literal horseshit. I'm sorry so much of your job is now dealing with metaphorical horseshit. Way grosser.)

@sundogplanets @mcnado They might be drawn to it because of the brain worms.
@jens @sundogplanets @mcnado We give it monthly to prevent heart worm in our dog. He’s fond of the chewable form…

@edsullivan @sundogplanets @mcnado yeah, I had to dose it accurately for pet rats from a tube of horse wormer paste. TL;DR is, I learned a lot about the dangers of overdosing (no animals suffered in this).

Which always makes me think about how likely it is for people who would use it on themselves for weird reasons to also get the dosage right, and what that means for their brain health.

@mcnado 6 years ago all it did was make stupid people clean out the supply of horse paste to "cure COVID" so it wasn't there for the people who actually needed it for its intended purpose: to kill off intestinal worms in livestock.

Dumshits.

@mcnado I think they should double up on whatever dosage they're taking. And then keep doubling up until it "works."

@mcnado I followed the Ivermecting story from hope to analysis to "not gonna work." Like theres a whole recorded history.

Yet people had to make goddamn horse paste a political signifier. Performative medicine.

@mcnado It was never an Okay theory. It's a horse dewormer. 🙄

@Scienceisnotopinions @mcnado before it had been properly investigated, it wasn't such a far-fetched idea that ivermectin could have off-target benefits like mitigating covid symptoms. after all, weirder things have turned out to be essential medicines, like the compounds produced by mould (penicillin). there are also some existing medicines that work, even though we don't know how (like lithium).

of course now we know that ivermectin is useless against covid. but dismissing unusual ideas without investigating them could mean leaving future cures undiscovered.

@ignova @mcnado I just hate that people are flocking to these wellness gurus who often have no medical background and a political agenda.

And yes, there are lots of things that benefit us that aren't talked about in main stream health. I just found out that gelatin helps build muscle if taken with vitamine C. And then there is the creatine benefits that have recently come up.

@mcnado

Okay, but wouldn't you agree that taking 8 quarts a day of tea brewed with swamp water and poison ivy and civet poop will prevent you from ever getting a virus?

Just joshing. Please don't firebomb my outhouse. 🥴

@mcnado

So...you're saying buy methylene blue from Alex Jones? Got it, thanks doc!

@mcnado
The Ivermectin lobby has been on fire since the COVID-19 pandemic. Ivermectin for everything and everybody!

@mcnado

I don't understand.
Why do people believe in a new form snake oil when it doesn't work?
Medicine by populist politics is a non-starter …

@mcnado I understand ivermectin will kill ear mites in cats.
@mcnado Much cheaper to drink own urine with orange juice, or raspberry cordial. Cheaper, and every bit as effective.
It's a virus.
@mcnado Well, at least they are not taking Hydroxychloriquine again (Last time I think they caused a shortage for people who actually need it).

@mcnado

Do I need to know about the OK theory?

@pinsk I don’t recall why, but multiple labs thought it might have antiviral effects. Multiple mechanisms were proposed, but none proven, and in vivo studies showed it doesn’t work. Also not harmful at normal doses, but ineffective.
@mcnado Meanwhile, ivermectin isn't approved worldwide for scabies, a thing in humans it actually solves.

@mcnado
Biology and medicine still remain domains where 100% precise information does not yet exist.

Where there is too much uncertainty, contradiction, and unverifiable hypotheses, fraud, manipulation, and false hopes inevitably appear.

That is why humanity needs systems built on maximum precise and verifiable information.

https://orcid.org/0009-0009-8968-3111

ORCID

@mcnado horseshit. Quite literally…
@mcnado @pluralistic
This got me thinking, what IS a better snake oil? I realized that it's probably something utterly without any effects at all, because at least it doesn't actively HARM the person taking it, like Ivermectin does.
@qole @mcnado @pluralistic I like the own urine plus something abundant way; pretty sustainable.

@mcnado Treated several cases in residency ? Ouch.

Which country are you based in ?
(Also, were the specific strains involved identified ? How was the rate of survival in your case.)

(And  for anyone preaching Ivermectin again)

@Sobex the Southwestern US has Sin Nombre virus, which causes classic hantavirus pulmonary syndrome. I don’t know the fatality rate off hand in our ICU, but it was significant. There was no timely test, so it was a guessing game using the clinical score put together by UNMH. Typically folks had a prolonged ICU stay, intubated and on renal replacement, until the ARDS, sepsis, or shock caught up with them.
@mcnado @Guillotine_Jones They should totally save their money for a Trump Mobile phone.

@mcnado from what I recollect the thinnest sliver of Ivermectin correlation came from a study done in the developing world.

The developing world it turns out, has a non-trivial amount of parasite hosting people. Which is what ivermectin was actually used for in veterinary medicine - treatment of intestinal parasites. So yeah, a statistically significant amount of people got better in these studies.

It took time to identify what was really going on in that study. All of this flies 7,000' above Joe Rogan's head and gets left completely out of the conversation happening around Ivermectin by then.

In the context of the hunta virus however... Just no. Like WTF stupid. It's flood the zone BS. Noise. Stupid shit to occupy the limited mental bandwidth of the bottom 1/2 of the bell curve.

@mcnado NO FUCKING JOKE ! We ( 4 weeks ago ) had to go through a mini-nightmare of red tape to GET MEDICINE FOR A SICK HORSE THAT NEEDED IT because "no I want the original paper", "no I want to speak with the vet", "no I need to receive this by mail first" .. and I'd bet it's precisely because of humans trying to get horse medications for their own use !! Yeah get <horse stuff> and end up anaemic and/or with your liver or else destroyed .. they are NOT made for human biology !
@mcnado pretty sure my village made a cocktail out of ivermectin for these asshats. Head on down to waterside and get you a wiggler on the roof.
@mcnado I absolutely love how it immediately resurfaced. These people are just so amazingly stupid.

@mcnado The real cure was announced in April 2020. It brings ultraviolet light inside the body, which should handle the virus more quickly than the release of the Epistein files.

As a backup, there are disinfectants such as bleach that can also go inside the body, maybe as an injection or something like that.

/s

Be sure to pray to the new golden calf statue once it works.