Short-term dietary changes can result in mucosal and systemic immune depression | Nature Immunology
Based on alternating on/off high fat diet in mice.
"We speculate that in order to guarantee efficient digestion of energy-dense nutrients, a transient downregulation of immunity might have been evolutionarily tolerated. However, this may have come at a price, creating windows of opportunities for pathogenic infections" #immunology #research #science #diet
Short-term dietary changes can result in mucosal and systemic immune depression - Nature Immunology
Here, the authors show that short-term consumption of energy-dense diets deficient in fiber, similar to eating patterns for many people today, results in a transient depression of the mucosal and systemic immune systems such that susceptibility to bacterial infection is increased.
