#COVID19 #VariantDashboard - #UnitedStates
TOP lineages (#15DAYTRENDS):
54.5% XBB.1.5
5.8% XBB.1.16
5.2% XBB.1.9.1
2.6% XBB.1.16.1
2.5% XBB.1.5.1
2.2% XBB.2.3
2.1% XBB.1.9.2
1.7% EG.1
#SARSCoV2 Tracker: http://tinyurl.com/mryj4uu7 Updated: 05/04/23
1/n
#COVID19 #VariantDashboard - #USA
[without "Airport Surveillance" sequences]
Top lineages (#15DayTrends):
XBB.1.5 (62.5%)
XBB.1.16 (3.4%)
XBB.1.9.1 (3.4%)
XBB.1.5.1 (2.6%)
XBB.1.5.13 (1.6%)
XBB.2.3 (1.5%)
FL.2 (1.3%)
EG.1 (1.1%)
FU.1 (1.1%)
XBB.1.16.1 (1.1%)
2/n
Airport sequences constitute ~19.5% of sequences with sample collection dates in the last 15 days (#15DayTrends)
Its going to be a three way race to outcompete XBB.1.5*: XBB.1.9* vs XBB.1.16* vs XBB.2.3*
As of now, XBB.1.16* family looks to over take everything else!
3/n
Sequence count by US States
#Texas has submitted a big share of sequences with specimen collection dates on or after 04/19/2023
XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16
4/n
.@CDCgov updated variant proportions estimates on 04/28/2023 (updated every Friday)
XBB.2.3* might make an entry tomorrow!
Prudent to start tracking EG.1*, XBB.1.16.1 as well
https://twitter.com/RajlabN/status/1651967457064628228
5/n
---
RT @RajlabN
SARSCoV2 #VariantProportions - #USA |04/28/23
New @CDCgov #Nowcast estimates:
Top circulating lineages:
XBB.1.5 (68.8%) ⬇️
XBB.1.16 (11.7%) ⬆️
XBB.1.9.1 (9%)
XBB.1.9.2 (3.7…
https://twitter.com/RajlabN/status/1651967457064628228
XBB.1.16 has the potential to outcompete all other circulating lineages.
Everyone is closely watching XBB.1.16 hotspots for clues
Tracker: https://public.tableau.com/app/profile/raj.rajnarayanan/viz/TrackingXBB_1_16LineageOverTime/XBB_1_16
6/n
XBB.1.16 is one of the fittest variant in circulation right now.. and is picking up additional mutations... "its the one to watch"
H/T @ErinMPrater @WellatFortune
@FortuneMagazine
https://fortune.com/well/2023/03/31/arcturus-covid-variant-watch-who-world-health-organization-xbb116-omicron-wave
7/n
Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)
Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.
Get updated if you haven't already!
https://public.tableau.com/app/profile/raj.rajnarayanan/viz/ImmuneEscapevsACE2BindingrelativetoBA2-USA15DayTrends/Dashboard2
8/n
.@CDCgov has authorized a second dose of the bivalent Omicron-BA.5 vaccine for older adults and immunocompromised adults
https://twitter.com/RajlabN/status/1648819491378192384
9/n
---
RT @RajlabN
.@CDCgov allows older adults and immunocompromised adults to get second dose of the bivalent Omicron-BA.5 vaccine https://twitter.com/CDCgov/status/1648798530767560707
https://twitter.com/RajlabN/status/1648819491378192384
#Hospital #Capacity - (by State/Division)
All hospitalizations not just COVID-19
https://public.tableau.com/app/profile/raj.rajnarayanan/viz/HospitalCapacity-USA/HospitalCapacity
10/n
#COVID19 #Hospitalizations in the #UnitedStates
>60 yr old & immunocompromised Have a good look at @CDCgov info on #Boosters!
#Ventilate Indoor spaces
Sick? --> Wear a good quality #Mask!
Hospital Tracker (by States, by age group):https://public.tableau.com/app/profile/raj.rajnarayanan/viz/COVID19HospitalizationsUSA/COVID19_HOSP_USA
11/n
Status of the latest #COVID19 Wave in #NewYork #Bellwether #State
XBB.1.5 is still the top circulating lineages in NY
[includes airport surveillance seqs]
12/n
Status of the latest #COVID19 Wave in #California
XBB.1.5 is still the top circulating lineage in CA (#15DayTrends) includes airport surveillance sequences
13/n
Status of the latest #COVID19 Wave in #Texas
XBB.1.5 is still the top circulating lineage in TX (#15DayTrends)
14/n
USA Airport surveillance update #15DayTrends
149 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia) from @CDCgov's Traveler-Based Genomic Surveillance Program.
*Includes pooled swabs & Many bad QC seqs
15/n
As COVID Tracking Wanes, Are We Letting Our Guard Down Too Soon? "Closing up shop too early could mean we are blindsided" “You have to maintain a base level of sequencing for new variants"
H/T @DohenyKathleen @WebMD
https://webmd.com/covid/news/20230411/are-we-letting-our-guard-down-on-covid-too-quickly
16/n
The next pandemic could be ‘as infectious as this one but far more lethal’—and make COVID look like a cakewalk, expert warns
H/T @ErinMPrater @WellatFortune
@FortuneMagazine
https://fortune.com/well/2023/04/26/next-pandemic-sars-cov-3-infectious-transmissibility-lethality-covid-mers-bird-flu/
17/n
"We don't have to feel pressured to move on from a real public health threat. We have a collective responsibility to protect our seniors and immunocompromised. Letting the virus spread unchecked is never a viable option."
H/T @filth_filler
https://salon.com/2023/05/02/as-mutates-the-vaccine-goalpost-has-shifted-to-preventing-severe-illness-and/
18/n
Raj Rajnarayanan 
