#COVID19 #VariantDashboard - #UnitedStates
TOP lineages (#15DAYTRENDS):
53.6% XBB.1.5
6.5% XBB.1.16
6.0% XBB.1.9.1
2.6% XBB.1.16.1
2.5% XBB.2.3
2.0% XBB.1.5.1
1.5% XBB.1.9.2
1.5% XBB.1.5.13
#SARSCoV2 Tracker: http://tinyurl.com/mryj4uu7 Updated: 04/26/23
1/n
#COVID19 #VariantDashboard - #USA
[without sequences from "Airport Surveillance"]
Top lineages (#15DayTrends):
XBB.1.5 (61.7%)
XBB.1.9.1 (5.1%)
XBB.1.16 (3.4%)
XBB.1.5.1 (1.9%)
XBB.1.5.13 (1.6%)
XBB.1.5.17 (1.6%)
XBB.1.16.1 (1.2%)
XBB.1.5.15 (1.2%)
XBB.2.3 (1%)
2/n
Airport sequences constitute a significant proportion of sequences (~20%) ie., #15DayTrends
If you remove these sequences, its a clear three way race to outcompete XBB.1.5:
XBB.1.9* vs XBB.1.16* vs XBB.2.3*
As of now, XBB.1.16* family looks to over take everything else!
3/n
Sequence count by US States
#California has submitted a big share of sequences with specimen collection dates on or after 04/11/2023
XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16
4/n
Granular details -#VariantDashboard #USA #15DayTrends
XBB.1.5* (VOI - @WHO) is still ahead of the other lineages!
5/n
.@CDCgov updated variant proportions estimates on 04/21/2023 (updated every Friday)
Prudent to start tracking EG.1* & XBB.2.3* as well
https://twitter.com/RajlabN/status/1649424522725019650
6/n
---
RT @RajlabN
#SARSCoV2 #VariantProportions - #USA |04/21/23
New @CDCgov #Nowcast estimates:
Top circulating lineages:
XBB.1.5 (73.6%)⬇️
XBB.1.16 (9.6%) ⬆️
XBB.1.9.1 (7.9%)
XBB.1.9.2 (2.9%)
XBB.1.5.1 (2.2%)
FD.2 (1.6%)…
https://twitter.com/RajlabN/status/1649424522725019650
XBB.1.16 has the potential to outcompete all other circulating lineages.
Everyone is closely watching XBB.1.16 hotspots for clues
Tracker: https://public.tableau.com/app/profile/raj.rajnarayanan/viz/TrackingXBB_1_16LineageOverTime/XBB_1_16
7/n
XBB.1.16 is one of the fittest variant in circulation right now.. and is picking up additional mutations... "its the one to watch"
H/T @ErinMPrater @WellatFortune
@FortuneMagazine
https://fortune.com/well/2023/03/31/arcturus-covid-variant-watch-who-world-health-organization-xbb116-omicron-wave
8/n
What to know about the XBB.1.16 COVID variant causing concern in India
H/T @ingridhein @medpagetoday
https://abcnews.go.com/Health/xbb116-covid-variant-causing-concern-india/story?id=98405058
9/n
Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)
Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.
Get updated if you haven't already!
https://public.tableau.com/app/profile/raj.rajnarayanan/viz/ImmuneEscapevsACE2BindingrelativetoBA2-USA15DayTrends/Dashboard2
10/n
.@CDCgov has authorized a second dose of the bivalent Omicron-BA.5 vaccine for older adults and immunocompromised adults
https://twitter.com/RajlabN/status/1648819491378192384
11/n
---
RT @RajlabN
.@CDCgov allows older adults and immunocompromised adults to get second dose of the bivalent Omicron-BA.5 vaccine https://twitter.com/CDCgov/status/1648798530767560707
https://twitter.com/RajlabN/status/1648819491378192384
#Hospital #Capacity - (by State/Division)
All hospitalizations not just COVID-19
https://public.tableau.com/app/profile/raj.rajnarayanan/viz/HospitalCapacity-USA/HospitalCapacity
12/n
#COVID19 #Hospitalizations in the #UnitedStates
>60 yr old & immunocompromised Have a good look at @CDCgov info on #Boosters!
#Ventilate Indoor spaces
Sick? --> Wear a good quality #Mask!
Hospital Tracker (by States, by age group):https://public.tableau.com/app/profile/raj.rajnarayanan/viz/COVID19HospitalizationsUSA/COVID19_HOSP_USA
13/n
Status of the latest #COVID19 Wave in #NewYork #Bellwether #State
Top circulating lineages in NY (#15DayTrends)
XBB.1.5 (45%)
XBB.1.16 (7.8%)
XBB.1.9.1 (5.4%)
XBB.1.5.1 (5.4%)
XBB.2.3 (5.4%)
XBB.1.16.1 (4.7%)
[includes airport surveillance seqs]
13/n
Status of the latest #COVID19 Wave in #California
Top circulating lineages in CA (#15DayTrends)
XBB.1.5 (46.7%)
XBB.1.9.1 (7%)
XBB.1.16 (5.8%)
XBB.2.3 (4.6%)
EG.1 (4.1%)
XBB.1.16.1 (2.5%)
XBB.1.9.2 (2.1%)
[includes airport surveillance sequences]
14/n
USA Airport surveillance update #15DayTrends
244 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia) from @CDCgov's Traveler-Based Genomic Surveillance Program.
*Includes pooled swabs & Many bad QC seqs
15/n
As COVID Tracking Wanes, Are We Letting Our Guard Down Too Soon?
"Closing up shop too early could mean we are blindsided" “You have to maintain a base level of sequencing for new variants"
H/T @DohenyKathleen @WebMD
https://webmd.com/covid/news/20230411/are-we-letting-our-guard-down-on-covid-too-quickly
16/n
The next pandemic could be ‘as infectious as this one but far more lethal’—and make COVID look like a cakewalk, expert warns
H/T @ErinMPrater @WellatFortune @FortuneMagazine
17/n
Raj Rajnarayanan 
LydiaLu
HFM