MiguelGF#ALT (not #telomerase) repairs damaged telomeres in #iPSCs… 😳 This finding comes in a sequences of others recognizing different
rules for #DNAdamage detection, #checkpoint activation and even #DNA repair in undifferentiated cells. 🧬👍
“Our findings suggest a previously unappreciated role for ALT in telomere maintenance in telomerase-positive iPSCs and reveal distinct iPSC-specific responses to targeted telomeric damage.” https://www.biorxiv.org/content/10.1101/2023.01.19.524780v1
rules for #DNAdamage detection, #checkpoint activation and even #DNA repair in undifferentiated cells. 🧬👍
“Our findings suggest a previously unappreciated role for ALT in telomere maintenance in telomerase-positive iPSCs and reveal distinct iPSC-specific responses to targeted telomeric damage.” https://www.biorxiv.org/content/10.1101/2023.01.19.524780v1
