Interesting facts about #hippos:

• it doesn't have true #sweat glands, and the secretion they secrete is what people call "blood sweat"

• despite it's name, this #secretion is neither #blood nor sweat. Instead, it's a blend of #hipposudoric #acid and #norhipposudoric acid (#protects against #bacteria)

• milk is white like all mammals, but their skin secretes a secretion that turns the milk pink

• it can even nurse underwater if it wishes

#zoology #science

“The divine consciousness which is reflected and refracted in the works of Genius feeds upon a certain secretion, as I believe. This secretion is analogous to semen, but not identical with it. There are but few men and fewer women, those women being invariably androgyne, who possess it at any time in any quantity. So closely is this secretion connected with the sexual economy that it appears to me at times as if it might be a by-product of that process which generates semen.”

https://library.hrmtc.com/2024/02/29/the-divine-consciousness-which-is-reflected-and-refracted-in-the-works-of-genius-feeds-upon-a-certain-secretion-as-i-believe-this-secretion-is-analogous-to-semen-but-not-identical-with-it-there/

"The divine consciousness which is reflected and refracted in the works of Genius feeds upon a certain secretion, as I believe. This secretion is analogous to semen, but not identical with it. There are but few men and fewer women, those women being invariably androgyne, who possess it at any time in any quantity. So closely is this secretion connected with the sexual economy that it appears to me at times as if it might be a by-product of that process which generates semen." - The Hermetic Library Blog

The divine consciousness which is reflected and refracted in the works of Genius feeds upon a certain secretion, as I believe. This secretion is analogous to semen, but not identical with it. There are but few men and fewer women, those women being invariably androgyne, who possess it at any time in any quantity. So […]

The Hermetic Library Blog

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Google Docs
Nanoplasmonic imaging reveals real-time protein secretion

EPFL researchers have used a nanoplasmonics approach to observe the real-time production of cell secretions, including proteins and antibodies; an advancement that could aid in the development of cancer treatments, vaccines, and other therapies.

Phys.org
We found that the #Parkinson's disease related kinase #LRRK2 interacts with vesicular #SNAREs #VAMP4 and #VAMP7. #VAMP4 and #VAMP7 are required for proper processing and release of #Parkinson's disease #biomarkers #VGF as we found using #secretomics. We found late endosomal #secretion of #VGF together with #exosome markers like #CD63. We also developed a #rushassay to study #VGF #trafficking.
Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREs

Filippini et al. report the direct interaction of leucine-rich repeat kinase 2 (LRRK2) with the endosomal vesicular SNAREs VAMP4 and VAMP7. LRRK2, VAMP4, and VAMP7 regulate the secretion of the Parkinson’s disease biomarker VGF. They provide evidence for the role of LRRK2 in regulating unconventional secretion in the disease.

Cell Reports
Unconventional #secretion of unglycosylated #ORF8 is critical for the #cytokine #storm during #SARS-CoV-2 infection https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011128
Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection

Author summary Cytokine storm is an important point in the transition of COVID-19 from mild to severe/critical diseases. Clinical cases show that the viral loads in patients are not directly proportional to the severity of disease symptoms, which indicates that in addition to virion release, there is a unique indirect cellular communication mechanism in the development of cytokine storm. In this study, we found that accessory protein ORF8 is a secretory protein that acts as messenger for the inter-cellular communication between alveolar epithelial cells (the main targets of virus) and monocytes/macrophages (the main executors of cytokine storm). Our findings are helpful to understand the occurrence of cytokine storm caused by SARS-CoV-2, and provide a potential strategy for COVID-19 therapeutic drugs.

Assembly and architecture of the type III #secretion sorting platform | PNAS

https://www.pnas.org/doi/10.1073/pnas.2218010119

#secretion : the act of secreting or concealing

- Italian: secrezione

- Portuguese: secreção

- Spanish: secreción

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#secretion : the act of secreting or concealing

- Italian: secrezione

- Portuguese: secreção

- Spanish: secreción

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