PLOS BiologyCells reallocate their limited energy for cellular maintenance in response to nutrient scarcity, but how? This study shows that the nucleolar RNA #exosome surveillance mechanism can be temporarily inhibited, reducing translation in #Celegans to adapt to starvation @PLOSBiology https://plos.io/3Zs1B6c
Inhibition of the nucleolar RNA exosome facilitates adaptation to starvation
Cells reallocate their limited energy for cellular maintenance in response to nutrient scarcity at the expense of other processes, but how this trade-off is achieved remains unknown. These authors show that the nucleolar RNA exosome surveillance mechanism can be temporarily inhibited reducing translation in C. elegans to facilitate adaptation to starvation.
Advancexo
Yuejin
Thierry Galli
Hao Yin