How did a cholera strain outwit viruses and ignite a major epidemic? The answer could redefine outbreak control. #cholera #phagetherapy #microbialdefense

https://geekoo.news/how-cholera-outsmarts-its-viral-predators/

How Cholera Outsmarts Its Viral Predators | Geekoo

EPFL researchers have decoded how cholera bacteria used viral immunity to fuel a deadly epidemic—reshaping our understanding of outbreaks and the future of phage therapy.

Geekoo

The Wildest Credible Ideas to Overcome Our Antibiotics Problems

The fight against antibiotic resistance is getting wild!

From phage therapy to microbiome manipulation, scientists are thinking outside the box.

What if these crazy ideas actually work? 🤔

Substack Podcast Version: tinyurl.com/29rz5t96

Youtube: youtu.be/c0FTHS244Cg

Home Base: airoad.substack.com

#AntibioticResistance #PhageTherapy #Antibiotics #Science

Unveiling bacteria's hidden defenses against viruses: Could this be the key to overcoming antibiotic resistance? Discover the groundbreaking research. #AntibioticResistance #Microbiology #PhageTherapy

https://geekoo.news/bacterias-secret-weapon-against-viruses-a-new-clue-in-combating-antibiotic-resistance/

Bacteria's Secret Weapon Against Viruses: A New Clue in Combating Antibiotic Resistance | Geekoo

Scientists at Umeå University have uncovered a novel bacterial defense mechanism against viruses, offering fresh insights into the battle against antibiotic resistance.

Geekoo
The first case of phage therapy for biliary tract infection caused by superbugs!

Biliary tract infections (BTI), often linked to structural abnormalities like bile duct stones, pose significant treatment challenges due to drug-resistant bacteria like Pseudomonas aeruginosa. Phage therapy, which uses viruses to target bacteria, has emerged as a promising solution. This study by researchers from Fudan University and Army Medical University, published in hLife, reported the first successful use of personalized phage therapy for chronic BTI caused by multidrug-resistant P. aeruginosa. An 88-year-old patent with recurrent infections underwent phage therapy after traditional treatments failed. A customized phage cocktail was administered, leading to symptom improvement and reduced bacterial load. However, phage-resistant strains emerged, prompting a second round of therapy with a different phage, which further alleviated symptoms. Genomic analysis revealed bacterial mutations contributing to resistance. This study highlights the potential of phage therapy for treating drug-resistant infections, though challenges like bacterial heterogeneity and biofilm formation remain. Future research aims to optimize phage therapy strategies for better outcomes.

EurekAlert!

"A century-old treatment that uses viruses to attack bacteria was successfully used in 2024 to save the life of a Singapore General Hospital (SGH) patient who had exhausted all care options for an antibiotic-resistant infection.

This made her the first patient in South-east Asia to benefit from phage therapy"

https://www.straitstimes.com/singapore/health/century-old-therapy-used-to-treat-sgh-patient-with-antibiotic-resistant-infection

#Bacteriophages #Health #Medicine #Singapore #Bacteria #PhageTherapy

Century-old therapy used to treat SGH patient with antibiotic-resistant infection

Known as phage therapy, it uses viruses to kill harmful bacteria in difficult-to-treat infections. Read more at straitstimes.com.

The Straits Times
Phage therapy - Wikipedia

🦠 Antibiotic-resistant bacteria are a growing problem. Can ‘bacteria-eaters’ help? A research team at #ChariteBerlin has now succeeded in training bacteriophages – viruses that ‘eat’ bacteria – in such a way that they can better combat the pathogen P. aeruginosa even behind its protective shield, the biofilm.

👉 https://www.charite.de/en/research/paper_spotlight/2024/new_findings_on_bacteria_eaters/

Because #PhageTherapy is still in its infancy: Please use #antibiotics cautiously!

@KunischFabian #medicine #science #AMR #FutureMedicine #ScienceMastodon

New findings on ‘bacteria-eaters’

Information on the range of services at Charité – Universtätsmedizin Berlin for patients, physicians, students and scientists

Personalized Phage Therapy Heals Cat With Deadly Bacterial Infection

"A persistent infection in a pet cat’s leg after a compound fracture was repaired has finally been cured using cutting-edge experimental medicine: personalized bacteriophage therapy."

by @grrlscientist via @medium

#pets #PhageTherapy #health #infection #ExperimentalMedicine #SciComm https://medium.com/gardening-birding-and-outdoor-adventure/personalized-phage-therapy-heals-cat-with-deadly-bacterial-infection-a46f19c11d7a

Personalized Phage Therapy Heals Cat With Deadly Bacterial Infection

A persistent infection in a pet cat’s leg after a compound fracture was repaired has finally been cured using cutting-edge experimental medicine: personalized bacteriophage therapy. What do you think…

Gardening, Birding, and Outdoor Adventure

11-JUL-2024
Researchers develop a way to make lifesaving #phages accessible, transportable and much easier to use
When #antibiotics fail, #bacteriophages can often save lives, but determining which ones will work and sourcing them is haphazard

https://www.eurekalert.org/news-releases/1051090
#science #PhageTherapy #bacteria #MicrobialEcology #medicine

Researchers develop a way to make lifesaving phages accessible, transportable and much easier to use

Researchers have developed a simple way to bring bacteriophage therapy into much closer reach for clinicians struggling to save patients with antimicrobial-resistant infections. The technology makes it possible to sort through hundreds or even thousands of phages in less than two hours to identify which will respond to a particular infection.  

EurekAlert!

Personalized Phage Therapy Heals Cat With Deadly Bacterial Infection, via Hebrew University, published by #Veterinary🩺 Quarterly

by @GrrlScientist

#Medicine⚕️ #PhageTherapy #Microbiology🔬 #MDRO #bacteria🧫 #bacteriophage🦠 #cats🐈‍⬛ #pets🐾 #SciComm🧪 https://www.forbes.com/sites/grrlscientist/2024/05/30/personalized-phage-therapy-heals-cat-with-deadly-bacterial-infection/

Personalized Phage Therapy Heals Cat With Deadly Bacterial Infection

A persistent infection in a pet cat’s leg after a compound fracture has finally been cured using cutting-edge experimental medicine: personalized bacteriophage therapy.

Forbes