Mastodawn

Identification of a small #chemical molecule that actively inhibits #bacterial immune defenses, enabling #bacteriophages to successfully infect and destroy #bacteria that would otherwise resist #viral attack.
#Biochemistry #Microbiology #sflorg
https://www.sflorg.com/2026/02/bchm02042601.html

Biochemistry lab at IU Bloomington finds chemical solution for tackling antibiotic resistance

Bacteriophages, the viruses that attack and kill bacteria, can be a useful alternative to antibiotics.

Technische Universität München Dec 23

In the German science program Quarks, Bärbel Stecher, professor of #IntestinalMicrobiome, explains how #bacteriophages target specific bacteria and their relevance for #AntibioticResistance and the #GutMicrobiome. Watch now: http://go.tum.de/112324

📷A.Eckert

Are phages the future of medicine?

Phages offer hope in the fight against resistant germs. TUM professor Bärbel Stecher provides insights into the current state of research.

Benjamin Carr, Ph.D. 👨🏻‍💻🧬Oct 30

#AI can now design functional #viruses - not the computer kind, either
Inject this synthetic #phage into #Ecoli and it kills better than the real thing
#Bacteriophages, are viruses that infect bacteria, have been widely studied since their discovery in the early 20th century. The end result of the AI portion of the project was a pool of 302 candidate #genomes, 285 of which were able to generate full genomes. Of those, 16 were found to inhibit growth of E. coli #bacteria.
https://www.theregister.com/2025/09/18/researchers_just_created_a_working/

AI can now design functional viruses – not the computer kind, either

: Inject this synthetic phage into E. coli and it kills better than the real thing

The Register

Bi Sasquatch Oct 1

Big Picture Science for Sep. 29, 2025: Not Just a Phage

REPEAT
We’re hurtling towards a post-antibiotic world, as the overuse of antibiotics has given rise to dangerous drug-resistant bacteria. Can we fight back using viruses as weapons? An obscure medical therapy uses certain viruses called bacteriophages to treat infection. For a century attempts to turn phage-therapy into a life-saving treatment have faltered, but today there’s renewed interest in this approach. Can we use phages to forestall the antibiotic crisis?

Guests:

* Claas Kirchhelle – Medical historian at the University College, Dublin
* Tom Ireland – Journalist, editor of The Biologist and author of “The Good Virus: The Amazing Story and Forgotten Promise of the Phage”
* Steffanie Strathdee – Associate Dean of Global Health Sciences at the University of California San Diego
* Tom Patterson – Professor of psychiatry at the University of California San Diego

Originally aired August 12, 2024

Download podcast at - https://bigpicturescience.org/episodes/not-just-a-phage

You can listen to this and other episodes at http://bigpicturescience.org/

Get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support!

#Antibiotics #Bacteria #Bacteriophages #BigPictureScience #SETI #News #Podcast #Science

Tadonic the Flautulent Sep 26, 2025

Could animal poo help fight drug‑resistant infections? | @Reuters https://www.youtube.com/watch?v=m406j4coRzs
#news #NoShit #biology #disease #bacteriophages #feces #disease #infection #prevention #cures #treatments

Could animal poo help fight drug‑resistant infections? | REUTERS

YouTube

René van de Vondervoort Aug 19, 2025

A bacteriophage is a virus that infects and replicates within bacteria. There are more bacteriophages on the planet than any other organism on Earth.
Bacteriophages are an alternative to antibiotics.

#art #visualart #contemporaryart #artist #contemporaryartist #sculpture #bacteriophages #mastoart #mastodonart #assemblage #antibiotics

Ganbatte Jun 28, 2025

an interesting article about bacteriophage and also a link to a free science exhibition happening july first to july sixth and a link to maybe you (not sure yet if it only applies to people in the uk) helping find a new phage 😃

#science #citizenscience #bacteriophages

https://www.bbc.com/news/articles/czryvm3nlvdo

Phage therapy: I found a bacteria-eating virus in my loo

It's hoped phages could give us new ways of treating infections which are immune to antibiotics.

Planetary Ecologist May 29, 2025

Phage display (Microbiology 🦠)

Phage display is a laboratory technique for the study of protein–protein, protein–peptide, and protein–DNA interactions that uses bacteriophages to connect proteins with the genetic information that encodes them. In this technique, a gene encoding a protein of interest is inserted into a phage coat protein gene, causing the phage to "di...

https://en.wikipedia.org/wiki/Phage_display

#PhageDisplay #Microbiology #Bacteriophages #MolecularBiology #DisplayTechniques

NIOO-KNAW Apr 4, 2025

New publication: #Nematodes vector #bacteriophages in #compost and #soil. #hitchhiking #dispersal #soil
https://doi.org/10.1016/j.soilbio.2025.109785

michael Apr 3, 2025

2-Apr-2025
The first case of #phageTherapy for biliary tract infection caused by #superbugs

https://www.eurekalert.org/news-releases/1079259 #science #medicine #microbiology #bacteriophages

The first case of phage therapy for biliary tract infection caused by superbugs!

Biliary tract infections (BTI), often linked to structural abnormalities like bile duct stones, pose significant treatment challenges due to drug-resistant bacteria like Pseudomonas aeruginosa. Phage therapy, which uses viruses to target bacteria, has emerged as a promising solution. This study by researchers from Fudan University and Army Medical University, published in hLife, reported the first successful use of personalized phage therapy for chronic BTI caused by multidrug-resistant P. aeruginosa. An 88-year-old patent with recurrent infections underwent phage therapy after traditional treatments failed. A customized phage cocktail was administered, leading to symptom improvement and reduced bacterial load. However, phage-resistant strains emerged, prompting a second round of therapy with a different phage, which further alleviated symptoms. Genomic analysis revealed bacterial mutations contributing to resistance. This study highlights the potential of phage therapy for treating drug-resistant infections, though challenges like bacterial heterogeneity and biofilm formation remain. Future research aims to optimize phage therapy strategies for better outcomes.

EurekAlert!