🧠 New paper by Safaai et al. (2025): parietal #cortex output populations show highly structured, task-dependent population geometry. Using multi-area recordings and circuit modeling, they show that #parietal populations display organized task-related patterns rather than uniform mixed coding, and that distinct output groups shape how decisions are routed to downstream targets:

🌍 https://doi.org/10.1038/s41593-025-02095-x

#Neuroscience #NeuralCoding #ParietalCortex #PopulationDynamics #DecisionMaking

How does what you know influence where you look? @TomRhysMarshall &co show that #parietal brain regions both resolve competition between options (‘where should I look next?’) and - via a different mechanism - integrate information from earlier experiences (‘what have I seen before?’) #PLOSBiology https://plos.io/3UjZgIH
The representation of priors and decisions in the human parietal cortex

How does what you know influence where you look? This study shows that parietal brain regions both resolve competition between options (‘where should I look next?’), and—via a different mechanism—integrate information from earlier experiences (‘what have I seen before?’).

Cortical thinning is associated with altered neurotransmission in young adults with a history of heavy drinking since adolescence

The article discusses a recent study conducted in Finland that explored the effects of #heavy #alcohol #consumption during #adolescence on #brain #development.

The study followed a group of young adults over a 10-year period, comparing those with a history of heavy drinking in adolescence to those who consumed little or no alcohol. The researchers found that the heavy-drinking group had #lower #cortical #gray #matter #thickness in several brain regions and #altered #neurotransmission compared to the control group.

Specifically, they observed increased activity in inhibitory neurotransmitters and thinner gray matter in the #frontal and #parietal lobes.

The study highlights the potential negative impact of heavy alcohol use during adolescence on brain structure and function, emphasizing the need for further research to understand the underlying mechanisms

| University of Eastern Finland

https://www.uef.fi/en/article/cortical-thinning-is-associated-with-altered-neurotransmission-in-young-adults-with-a-history-of

Cortical thinning is associated with altered neurotransmission in young adults with a history of heavy drinking since adolescence

During adolescence, the brain is particularly susceptible to the deleterious effects of alcohol use.

University of Eastern Finland