🐭🎶 New paper by Isko et al, who study #Alston’s singing mouse, a rodent with loud, stereotyped songs.

Using bulk tracing, serial #2P #tomography, & #MAPseq of >76,000 barcoded neurons, they find expanded projections from #orofacial #MotorCortex to #auditory #cortex & #PAG. This suggests that singing / #Vocalization may emerge not from entirely new circuits, but from selective strengthening of existing motor, auditory & vocal-control pathways.

📝 https://doi.org/10.1038/s41586-026-10458-y

#Neuroscience #Evolution

Enhanced motor cortical connections underlie vocal behavior in singing mice

📰 Original title: Specific expansion of motor cortical projections in a singing mouse

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/enhanced-motor-cortical-connections-underlie-vocal-behavior-in-singing-mice/?redirpost=c06e1ece-3c54-450b-916f-24dfd817bee6&utm_source=mastodon_world&utm_medium=social&utm_campaign=killbait

#neuroscience #motorcortex #voca...

Enhanced motor cortical connections underlie vocal behavior in singing mice

📰 Original title: Specific expansion of motor cortical projections in a singing mouse

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/enhanced-motor-cortical-connections-underlie-vocal-behavior-in-singing-mice/?redirpost=c06e1ece-3c54-450b-916f-24dfd817bee6&utm_source=mastodon_social&utm_medium=social&utm_campaign=killbait

#neuroscience #motorcortex #voc...

🧠 New work by Codol et al. who show that #MotorCortex dynamics are remarkably conserved across #mice, #monkeys, and #humans. Despite very different #behaviors, #NeuralPopulation activity follows similar dynamical rules on low-dimensional #manifolds. Species differences arise mainly from the geometry of trajectories within this shared #DynamicalSystem.

📄 https://doi.org/10.64898/2026.03.06.709637

#Neuroscience #CompNeuro #NeuralDynamics

There is a new episode on the #TheoreticalNeurosciencePodcast on low-dimensional #manifolds in #MotorCortex with Sara Solla ✌️, one of the pioneers of the manifold modelling approach in #Neuroscience.

🌍 http://theoreticalneuroscience.no/thn36

#CompNeuro #ComputationalNeuroscience

There's a great talk by Juan Gallego on how low-dimensional #NeuralManifolds arise from biological constraints, remain invariant across states and inputs, and support cross-animal alignment. Examples span #HeadDirection rings, #gridcell tori, #MotorCortex prep vs movement, striatal timing dynamics, and C. elegans #behavior loops. Cool talk as it shows how #manifold-level structure can generalize across tasks and organisms.

🌍 https://www.youtube.com/watch?v=oxQyKByqDSU

#CompNeuro #Neuroscience #PopulationDynamics

🧠 New preprint by Codol et al. (2025): Brain-like #NeuralDynamics for #behavioral control develop through #ReinforcementLearning. They show that only #RL, not #SupervisedLearning, yields neural activity geometries & dynamics matching monkey #MotorCortex recordings. RL-trained #RNNs operate at the edge of #chaos, reproduce adaptive reorganization under #visuomotor rotation, and require realistic limb #biomechanics to achieve brain-like control.

🌍 https://doi.org/10.1101/2024.10.04.616712

#CompNeuro #Neuroscience

🧠 New preprint by Kashefi et al. (2025): High-density #Neuropixels recordings in monkeys reveal compositional #NeuralDynamics in #MotorCortex. A posture subspace anchors fixed points, rotational dynamics link them to generate movement, and a uniform shift tracks trial state. Recurrent models show this geometry emerges only when controlling a full arm, suggesting posture-dependent control as a core principle:

🌍 https://www.biorxiv.org/content/10.1101/2025.09.04.674069v1

#Neuroscience #MotorControl #CompNeuro