NIOO-KNAWJun 5
New publication: The elephant (bird) in the room: unknown mechanisms and unresolved impacts of low #DNA yields in avian microbiome research. #birds #DNAextraction #hostmicrobiomeinteractions
https://doi.org/10.1186/s42523-026-00579-0
Jan TaubenheimJun 3, 2025

Our (@kaletalab) new study uncovers multi-level metabolic disruptions in #IBD involving reduced #HostMicrobiomeInteractions.

Elevated tryptophan catabolism → NAD biosynthesis impaired.

Disrupted nitrogen homeostasis affects polyamine/glutathione metabolism.

Suppressed C1 cycle alters NAD/phospholipid profiles.

#MetabolicModeling predicts dietary interventions to restore #Microbiome balance.

Read and share: https://rdcu.be/eo7B3
#SystemsBiology #Microbiome #MultiOmics #CAU #UKSH #Kiel