Researchers discover two vesicle fusion mechanisms while studying vesicle movement in living cells
Cells intake substances from the outside world by encapsulating them in vesicles called endosomes, which are subsequently transported throughout the cell. During the transport process, vesicles fuse with other intracellular organelles. However, observing this process is challenging in many cells due to their small size and the complexity of underlying regulatory mechanisms.
#Influenza virus infection triggers condensation of host recycling
#endosomes next to the ER. @SilviaValeCosta @mjamorim1 &co show that this a regulated process involving ATG9A, which detaches recycling endosomes from
#microtubules near the ER
#PLOSBiology https://plos.io/3QR78hJ 
ATG9A regulates the dissociation of recycling endosomes from microtubules to form liquid influenza A virus inclusions
Influenza A virus infection can trigger condensation of host recycling endosomes adjacent to the endoplasmic reticulum. This study shows that this a regulated process involving ATG9A, which facilitates the detachment of recycling endosomes from microtubules near the ER, revealing a novel role for ATG9A beyond autophagy.
New probe aids novel findings on cell functions
Collaborative research at the University of Cincinnati has developed a new probe to better study cells that has already led to new knowledge about certain cellular processes.
CellBioNews
PLOS Biology