In heterogeneous syndromes like ARDS and sepsis, I believe we generally are more likely to be able to find what causes iatrogenic harm than actual therapies. #emimcc #critcaresky

RE: https://bsky.app/profile/did:plc:q5ogl3twkcqyhvz4zebonw3z/post/3migjy6ta5z2u

Precision medicine in sepsis = correct antimicrobial coverage, source control and tailored haemodynamic support. #emimcc

RE: https://bsky.app/profile/did:plc:u6ai4u2rvrdb5xjk62y2jpci/post/3mjflldtrf52m

In a patient with high-risk pulmonary embolism, but no sign of hypoperfusion, would you start LMWH or UFH? #emimcc #cardisky #cccsky #critcaresky

On the other hand, if you use PICCO just to get the ABP value, you may become wiser #emimcc

RE: https://bsky.app/profile/did:plc:pdj5upxe4ocjvjltlkdai7b4/post/3miyx7rlbyc2r

TIGRIS, the new Xigris? #emimcc

RE: https://bsky.app/profile/did:plc:mciolqc63d6o6pveql6t6s2t/post/3mhycedhdyk22

The most dangerous thing you can have is a non-septic shock misclassified as septic shock. #emimcc

Can we please stop referring to lactate as a perfusion marker? It’s no more so and no better than blood pressure. #emimcc #cccsky

One point that isn't mentioned here but too often forgotten when noradrenaline seemingly isn't working: Are you actually using a representative blood pressure? Not so rare that a better (more central or better line) fixes the problem. Look at the whole patient, not just a number! #emimcc #cccsky

RE: https://bsky.app/profile/did:plc:vmwckmxogx3lipqxlmn76mbe/post/3mh67jqfw3z2h

The end of the road for rivaroxaban? Shows how important direct comparative trials among drugs within the same pharmacologic class are. #emimcc #cardiosky www.nejm.org/doi/full/10....

One thing that strikes me from these guidelines (which do have many good parts) is how many of the interventions have strong Ia recommendations based on purely observational evidence. Putting the cart before the horse #emimcc #cardiosky

RE: https://bsky.app/profile/did:plc:pdj5upxe4ocjvjltlkdai7b4/post/3mfi3rdpwyc2t