Cool study - an amp of sodium bicarbonate (50 ml 8.4%) raises sodium similar to a boils of 3% - as expected of course! pubmed.ncbi.nlm.nih.gov/41937305/ @[email protected] @[email protected] #nephsky #emimcc

Comparison of 8.4% Sodium Bica...
Comparison of 8.4% Sodium Bicarbonate vs. 3% Sodium Chloride in Severe Hyponatremia: A Retrospective Cohort Study - PubMed

This study found that a single 50 mL dose of HTB more often resulted in obtainment of guideline-recommended post-intervention serum sodium goal concentrations than a 100 mL HTS dose. Additional studies are needed to confirm these findings and provide a more comprehensive assessment of safety and eff …

PubMed
Tomorrow! Stephen McAdoo from Imperial College on anti-GBM disease #NephGR #NephSky
Happening tomorrow! @[email protected] from McMaster will present on eGFR changes as outcomes of interest #NephGR #NephSky
Also see: editorial from Heather Reich and @[email protected] in @[email protected] synthesizing the data on enteric coated budesonide www.kireports.org/article/S246... Nothing special about Nefecon IMO (like ACTHAR!) #NephSky

Enteric and Controlled-Release...
More badness uncovered here - today’s FDA warning Some fatal case of DLI and several VBDS They are recommending more frequent LFTs while starting Avacopan www.fda.gov/media/191708... This does not look good! #NephSky
File this under - trials that will never get done (Like spironolactone versus nsMRA or ASI Or voclosporin versus cyclosporine/tacrolimus) cc @[email protected] #NephSKy #ISNWCN
Interesting trial in @[email protected] www.kidney-international.org/article/S008... SLE with remission. No symptoms. When dsDNA becomes positive (or doubles) do you preemptively increase immunosuppression? #NephSky #RheumSky
Happening today! James Burton from Leicester will be presenting on in centre nocturnal dialysis #NephGR #NephSky