Swapnil Hiremath 🍁🇨🇦
In this edition, @[email protected] breaks down the Bayesian voodoo behind removing evil humor www.nephjc.com/news/2026/sh... #EMIMCC #NephSky

NephJC Short: Bayesian leash:...
NephJC Short: Bayesian leash: How a prior walked the Tigris across the finish line — NephJC

Can polymyxin B hemadsorption truly shift the fate of septic shock, or is the outcome already written?

NephJC
May 15 at 1:36amWeb
Show threadLars Mølgaard SaxhaugMay 15
I think the open label design is a much larger problem than the bayesian one.
Show threadMike JohansenMay 15
me too. Additionally- Bayesianism is a bad idea when you are just running a non-inferiority trial by another name.
Show threadSwapnil Hiremath 🍁🇨🇦May 15
On that note: the preceding EUPHRATES (from which the subgroup was picked for the priors) was sham controlled - we were a site and it was nicely done pmc.ncbi.nlm.nih.gov/articles/PMC... Also note there is little overlap in between the academic lead authors for EUPHRATES and TIGRIS 😎

Effect of Targeted Polymyxin B...
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Show threadSwapnil Hiremath 🍁🇨🇦5d ago
In @[email protected] today on the FDA and Bayesian trials jamanetwork.com/journals/jam...