@hswapnil

679 Followers
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105 Posts
MD, MPH, Assoc. Prof Univ of Ottawa, Nephrologist 
:renal:
#NephJC co-founder
NSMC internship Faculty 
Freely Filtered 🎙️panelist
Swapnil ‘Hee-Ray-mutth’
He/Him/His
Unceded territory of the Anishinaabe Algonquin Nation
Personal Pagehttps://www.swapnilhiremath.com/
Google Scholarhttps://scholar.google.ca/citations?user=wiHTA24AAAAJ&hl=en
Pubmedhttps://www.ncbi.nlm.nih.gov/myncbi/swapnil.hiremath.1/bibliography/public/?sortby=pubDate&sdirection=descending

B-cell modulations keep advancing

Telitacicept and albuminuria in IgAN in the NEJM

https://www.nejm.org/doi/full/10.1056/NEJMoa2514415

Interesting methods to tease out AKI from contrast from underlying sickness

They call it self control case series - but it’s like a case-crossover design?
https://www.kireports.org/article/S2468-0249(26)02832-9/fulltext

Interesting frailty intervention trial
Comprehensive geriatric assessment and intervention (see pic) improves frailty indices - Fried scale - but not hospitalization or mortality (though a bit lower and not powered for those secondary outcome)

https://www.kireports.org/article/S2468-0249(26)02827-5/fulltext

Agree with this

All formulae for corrected calcium are imperfect

Just measure ionized calcium

https://pubmed.ncbi.nlm.nih.gov/42035248/

#EMIMCC

Albumin-adjusted ("corrected") calcium should no longer be reported: a position statement from the Joint IOF Working Group and IFCC Committee on Bone Metabolism and EFLM Committee on CKD - PubMed

Albumin-adjusted ("corrected") calcium should no longer be reported: a position statement from the Joint IOF Working Group and IFCC Committee on Bone Metabolism and EFLM Committee on CKD

PubMed

Flozins and Fungi blocking the flow, fixed by fluconazole

(The authors title is quite boring!)

https://www.kidney-international.org/article/S0085-2538(26)00317-0/fulltext

Renal image in KI

https://www.kidney-international.org/article/S0085-2538(26)00320-0/fulltext

Actinomyces in the kidney from a ….toothpick?

Comprehensive review on the spectrum of tubulointerstitial disease from Lynn Cornell

https://www.kidney-international.org/article/S0085-2538(26)00326-1/fulltext in Kidney International

The effects of Obamacare on mortality, pre dialysis care, transplant and home dialysis rates

Before and after study caveats - in JAMA Peds ($reqd)

https://jamanetwork.com/journals/jamapediatrics/article-abstract/2848765

Medicaid Expansion and 1-Year Mortality Among Young Adults Initiating Dialysis

This cohort study uses a difference-in-differences design to examine data for young adults with kidney failure and determine whether Medicaid expansion under the Affordable Care Act was associated with lower mortality at 1 year.

@hswapnil

In Germany, drugs with a narrow therapeutic window are on a special list with the beautiful name „Substitutionsausschlussliste“.

As CNIs are on this list, a prescribing doctor must provide the exact generic brand which the pharmacists then must hand out.

Immunosuppressants in general are spared of the cost-monitoring systems which in other health areas insurances like to use a lot…

My colleague and a local patient in the news
Is Advagraf the same as generic?

https://www.ctvnews.ca/ottawa/article/ottawa-man-says-insurance-company-refuses-to-reimburse-for-brand-name-drug-despite-doctors-note/

Meanwhile the ODB website considers Advagraf interchangeable with sandoz-tacrolimus XR (see pics:)