B-cell modulations keep advancing
Telitacicept and albuminuria in IgAN in the NEJM
B-cell modulations keep advancing
Telitacicept and albuminuria in IgAN in the NEJM
Interesting methods to tease out AKI from contrast from underlying sickness
They call it self control case series - but it’s like a case-crossover design?
https://www.kireports.org/article/S2468-0249(26)02832-9/fulltext
Interesting frailty intervention trial
Comprehensive geriatric assessment and intervention (see pic) improves frailty indices - Fried scale - but not hospitalization or mortality (though a bit lower and not powered for those secondary outcome)
https://www.kireports.org/article/S2468-0249(26)02827-5/fulltext
Agree with this
All formulae for corrected calcium are imperfect
Just measure ionized calcium

Albumin-adjusted ("corrected") calcium should no longer be reported: a position statement from the Joint IOF Working Group and IFCC Committee on Bone Metabolism and EFLM Committee on CKD
Flozins and Fungi blocking the flow, fixed by fluconazole
(The authors title is quite boring!)
https://www.kidney-international.org/article/S0085-2538(26)00317-0/fulltext
Renal image in KI
https://www.kidney-international.org/article/S0085-2538(26)00320-0/fulltext
Actinomyces in the kidney from a ….toothpick?
Comprehensive review on the spectrum of tubulointerstitial disease from Lynn Cornell
https://www.kidney-international.org/article/S0085-2538(26)00326-1/fulltext in Kidney International
The effects of Obamacare on mortality, pre dialysis care, transplant and home dialysis rates
Before and after study caveats - in JAMA Peds ($reqd)
https://jamanetwork.com/journals/jamapediatrics/article-abstract/2848765

This cohort study uses a difference-in-differences design to examine data for young adults with kidney failure and determine whether Medicaid expansion under the Affordable Care Act was associated with lower mortality at 1 year.
In Germany, drugs with a narrow therapeutic window are on a special list with the beautiful name „Substitutionsausschlussliste“.
As CNIs are on this list, a prescribing doctor must provide the exact generic brand which the pharmacists then must hand out.
Immunosuppressants in general are spared of the cost-monitoring systems which in other health areas insurances like to use a lot…
My colleague and a local patient in the news
Is Advagraf the same as generic?
Meanwhile the ODB website considers Advagraf interchangeable with sandoz-tacrolimus XR (see pics:)