"Veronika Koren talks about pursuing a theory of neural coding that doesn’t fit a simple narrative, and the resilience it took to see it through."
https://elifesciences.org/inside-elife/75921c16/inside-discovery-where-theory-meets-biology

Q: "The first version of the article was described as "Incomplete" in the eLife Assessment. How did you feel about this, and what changes did you make to take that assessment to “Convincing”?"

A: "Our paper does not have a simple storyline but rather draws a somewhat intricate but deep link between a mathematical theory and the functioning of biological neural networks. We were worried that many journals would prefer a simpler "story", but estimated that eLife might be one that simultaneously enjoys an excellent reputation and where our results might be appreciated. [...] I was disappointed by the first assessment, because we omitted more detailed analyses to make the paper more focused. [...] the thorough reviews asked us to dig deeper, which we gladly did. I followed every comment of each reviewer with great attention, significantly reshaping the paper and making it more solid."

Indeed, at eLife we want the full enchilada. As it should be.

#neuroscience #eLife #eLifeAssessment

"Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation" Elizabeth Marin et al. 2024
https://elifesciences.org/reviewed-preprints/97766

"This fundamental study provides a near-comprehensive anatomical description and annotation of neurons in a male Drosophila ventral nerve cord, based on large-scale circuit reconstruction from electron microscopy. This connectome resource will be of substantial interest to neuroscientists interested in sensorimotor control, neural development, and analysis of brain connectivity. However, although the evidence is extensive and compelling, the presentation of results in this very large manuscript lacks clarity and concision."

#Drosophila #neuroscience #connectomics #eLifeAssessment