PRDM9 drives the location and rapid evolution of recombination hotspots in salmonid fish
Marie Raynaud, etal.
Brilliant study and fascinating biology
#Rapid #Evolution of the #prdm9 genes, and the hotspots
#salmonid #qtl #genetics #wgd @PLOSBiology
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002950
PRDM9 drives the location and rapid evolution of recombination hotspots in salmonid fish
PRDM9 is a DNA-binding protein that helps determine the location of recombination hotspots in many mammals. This study of several species of salmonid fish reveals that PRDM9 function is conserved across vertebrates and that the peculiar evolutionary runaway caused by PRDM9 has been active for several hundred million years.