StructBiolCommunicationsUnlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization https://t.co/ilB7Aa3Krg
Crystallization and crystallographic studies of human serine protease inhibitor (serpin) B9
This study successfully determined the crystal structure of human serpin B9 at 1.9 Å resolution and identified notable structural differences surrounding helix D, providing a potential target for the development of anticancer therapeutics.
RICARDO
Atelier de Luz
Fernando Antunes Amaral