🧩 Could structural AI finally decode the complex language of T-cell antigen recognition?

🔗 STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.09.004

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #ProteinLanguageModels #Immunotherapy #ComputationalBiology #Bioinformatics #MachineLearning #Immunology #ProteinEngineering #TCR #HLA #DrugDiscovery #AI

🤖 Are protein language models the next revolution in functional genomics?

🔗 Fine-tuning protein language models to understand the functional impact of missense variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.022

📚 CSBJ: https://www.csbj.org/

#Genomics #AI #ProteinLanguageModels #Bioinformatics #PrecisionMedicine #PLM #MissenseVariants #MachineLearning #ClinicalGenetics #AIinHealthcare #InterpretableAI #VariantInterpretation