Hey folks  

Bit of an odd practical biochemistry question in relation to the absorption speed of any meds.

Hypothetically-speaking, is it possible to turn an instant release (IR) med into an extended-release¹ (ER) version via non-commercial means?

Examples of IR meds might include:

• A capsule (designed to dissolve in the stomach) containing an easily-absorbed powder.
• A tablet without any coating and a structure that dissolves very easily.

Examples of ER meds we've seen include:

• Capsules containing tiny pellets, coated with something to slow absorption.
• Tablets with a coating designed to slow absorption.

Could you, for example:

• Encase the capsule in a larger, acid-resistant / enteric capsule?
  • e.g., like the ones described here
• Coat the tablet in some kind of food-safe coating?

Genuinely asking here, as we neither have the spoons nor time to go down an AuDHD rabbit hole investigating this 😅

#biochemistry #AskFedi #GenuinelyAsking #NoReplyGuysPlease

¹ aka prolonged, sustained, modified, or controlled release

Hey all  

We had another linguistic thought.

(You can see our previous linguistic queries on looking for words for the pain of being misunderstood and finding an alternative word for hope.)

We realised that English has a specific word for the inability to experience pleasure from activities you'd usually enjoy: anhedonia.

However, it doesn't seem like there's an equivalent official word for the inability to experience hope.

Instead, there are only words like hopeless or hopelessness, but those words do not really suggest that the person can no longer derive hope from situations they'd normally expect to.

Following the same logic as the above, we think it would be something like an- plus either elpĭ́s or elpída.

So, we think it'd be either anelpis or anelpida.

Thoughts? Suggestions? Corrections?

#AskFedi #GenuinelyAsking #NoReplyGuysPlease #English #linguistics #hope #hopeless #hopelessness #anelpis #anelpida

Random tech question, especially for audiophiles, or anybody who listens a lot to music.

What affordable (<=£50 GBP)¹ options exist in the UK for:

• Taking sound input from a sound card via a 3.5 mm audio cable or optical cable output;
• Transmitting the sound to paired bluetooth headphones; ...

... and which has a volume control option (ideally analogue, or otherwise at least 100 volume steps)?

We have bluetooth headphones (Sony WH-1000XM4), but only presently use the bluetooth connection when listening to music on our phone.

When we're at our PC, we've been using a 3.5 mm output from our speakers. We got those speakers back when we used to listen to music occasionally out loud, but we don't ever do that any more: we only listen via headphones, so the speakers are entirely redundant.

We'd like to be able to connect our headphones quickly to the PC with an analogue volume control, like the one we have on our current speakers.

In case it's relevant, we have a Sound Blaster Z sound card.

Boosts and quotes appreciated, if you think it'll help  

Please remember we're in the UK and looking to get something on a budget.

#AskFedi #tech #GenuinelyAsking #NoReplyGuysPlease #audio #audiophile

¹ This is the ideal price range, but if there's some longer-term better solution, perhaps involving a replacement PCI-E sound card that has a native option for this, or some device that might also help with future streaming stuff, if we can ever return to it, we're willing to consider the options presented. Anything beyond £100 GBP will be pushing it though, unless it's a perfect, long-term solution with multiple features.