Show threadBallouLabOct 16, 2024
Second, @AlyssaHudson83 showed that the TG11 antibody binds similarly to a wide range of important clinical isolates of #mucormycosis including #Rhizopus, #Lichtheimia, #Cunninghamella, and #Mucor species 10/ https://bit.ly/4eG3lyz
Characterization of the Spatiotemporal Localization of a Pan-Mucorales–Specific Antigen During Germination and Immunohistochemistry

A pan-Mucorales antibody binds to germinating hyphae and can discriminate Mucorales and Aspergillus hyphae by immunohistochemistry.

OUP Academic
Gabriele PollaraAug 23, 2023

Pretty exciting to see oral amphotericin behaving comparably to IV amphotericin for #HIV associated #Cryptococcus #meningitis

Phase 2 open label #RCT, so not quite there yet, but big potential win in simplicity and access to treatment for
#Cryptococcusneoformans & other #fungal diseases, potentially even #mucor

#infectiousdiseases #mycology #IDMastodon #MedMastodon #medicine @infectiousdiseases

https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciad440/7246927

Oral Lipid Nanocrystal Amphotericin B for Cryptococcal Meningitis: A Randomized Clinical Trial

A new oral amphotericin B lipid nanocrystal formulation appears promising for cryptococcal meningitis with similar quantitative antifungal activity in human CSF

OUP Academic
Microbiology Journal ClubAug 2, 2023

#alt4u

Lactophenol cotton blue stained #Mucor sp. There are blue stained #hyphae without clear septa poking out from a tangled core. The core is full of mature and immature #sporangia looking like smooth round structures and collections of small spores respectively. The tangle has a little more purple to it. One prominent hypha ends in a smooth immature sporangia.

@pathout