These conditions often create a cycle where mitochondrial dysfunction worsens the disease and the disease further damages mitochondria.
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The Keys to Understanding Mitochondrial Dysfunction
Let's explore the key factors that cause or contribute to mitochondrial dysfunction and some of the top supplements that can help mitochondria work better.
Dr. Pamela Frank, ND | Naturopath | Toronto, Ontario - Toronto Naturopath for Hormone and Digestive HealthMitochondrial dysfunction can lead to various health issues, but certain supplements may help improve mitochondrial function and support overall health.
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The Keys to Understanding Mitochondrial Dysfunction
Let's explore the key factors that cause or contribute to mitochondrial dysfunction and some of the top supplements that can help mitochondria work better.
Dr. Pamela Frank, ND | Naturopath | Toronto, Ontario - Toronto Naturopath for Hormone and Digestive HealthVielleicht wird #LongCoVID ernster genommen, wenn wir es #BioBlackout nennen? Das Mem "Mitochondrien sind Kraftwerke der Zelle" dΓΌrfte ja bei Vielen schon verankert sein.
> Novel biomarkers of #mitochondrialdysfunction in Long #COVID patients
> β¦ prolonged disruptions[of] cellular energy metabolism
> -- https://link.springer.com/article/10.1007/s11357-024-01398-4
#Blackout #SarsCoV2 #SARS_COV_2 #CoVIDisNotOver #dieMasteBleibtAuf #BrainFog #Hirnnebel #KraftwerkederZelle

Novel biomarkers of mitochondrial dysfunction in Long COVID patients - GeroScience
Coronavirus disease 2019 (COVID-19) can lead to severe acute respiratory syndrome, and while most individuals recover within weeks, approximately 30β40% experience persistent symptoms collectively known as Long COVID, post-COVID-19 syndrome, or post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC). These enduring symptoms, including fatigue, respiratory difficulties, body pain, short-term memory loss, concentration issues, and sleep disturbances, can persist for months. According to recent studies, SARS-CoV-2 infection causes prolonged disruptions in mitochondrial function, significantly altering cellular energy metabolism. Our research employed transmission electron microscopy to reveal distinct mitochondrial structural abnormalities in Long COVID patients, notably including significant swelling, disrupted cristae, and an overall irregular morphology, which collectively indicates severe mitochondrial distress. We noted increased levels of superoxide dismutase 1 which signals oxidative stress and elevated autophagy-related 4B cysteine peptidase levels, indicating disruptions in mitophagy. Importantly, our analysis also identified reduced levels of circulating cell-free mitochondrial DNA (ccf-mtDNA) in these patients, serving as a novel biomarker for the condition. These findings underscore the crucial role of persistent mitochondrial dysfunction in the pathogenesis of Long COVID. Further exploration of the cellular and molecular mechanisms underlying post-viral mitochondrial dysfunction is critical, particularly to understand the roles of autoimmune reactions and the reactivation of latent viruses in perpetuating these conditions. This comprehensive understanding could pave the way for targeted therapeutic interventions designed to alleviate the chronic impacts of Long COVID. By utilizing circulating ccf-mtDNA and other novel mitochondrial biomarkers, we can enhance our diagnostic capabilities and improve the management of this complex syndrome.
SpringerLinkAge-related decline in mitochondrial function is partly due to accumulated damage from oxidative stress & reduced efficiency in mitochondrial repair mechanisms.
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The Keys to Understanding Mitochondrial Dysfunction
Let's explore the key factors that cause or contribute to mitochondrial dysfunction and some of the top supplements that can help mitochondria work better.
Dr. Pamela Frank, ND | Naturopath | Toronto, Ontario - Toronto Naturopath for Hormone and Digestive HealthA combination of healthy lifestyle choices, proper nutrition, & minimizing exposure to environmental toxins supports mitochondrial function.
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The Keys to Understanding Mitochondrial Dysfunction
Let's explore the key factors that cause or contribute to mitochondrial dysfunction and some of the top supplements that can help mitochondria work better.
Dr. Pamela Frank, ND | Naturopath | Toronto, Ontario - Toronto Naturopath for Hormone and Digestive HealthFree radicals can damage mitochondrial membranes and DNA, leading to dysfunction.
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The Keys to Understanding Mitochondrial Dysfunction
Let's explore the key factors that cause or contribute to mitochondrial dysfunction and some of the top supplements that can help mitochondria work better.
Dr. Pamela Frank, ND | Naturopath | Toronto, Ontario - Toronto Naturopath for Hormone and Digestive HealthLack of physical activity, poor diet, smoking, excessive alcohol consumption, and chronic stress can all contribute to mitochondrial dysfunction.
Read more π https://lttr.ai/AVCZh
#MitochondrialDysfunction #mitochondria #Carnitine #Coq10 #Curcumin #Wellness

The Keys to Understanding Mitochondrial Dysfunction
Let's explore the key factors that cause or contribute to mitochondrial dysfunction and some of the top supplements that can help mitochondria work better.
Dr. Pamela Frank, ND | Naturopath | Toronto, Ontario - Toronto Naturopath for Hormone and Digestive Health
The Keys to Understanding Mitochondrial Dysfunction
Let's explore the key factors that cause or contribute to mitochondrial dysfunction and some of the top supplements that can help mitochondria work better.
Dr. Pamela Frank, ND | Naturopath | Toronto, Ontario - Toronto Naturopath for Hormone and Digestive HealthChronic exposure to environmental pollutants and radiation can also increase oxidative stress, which damages mitochondrial DNA and impairs function.
Read more π https://lttr.ai/AUxRY
#MitochondrialDysfunction #mitochondria #Carnitine #Coq10 #Curcumin #Wellness

The Keys to Understanding Mitochondrial Dysfunction
Let's explore the key factors that cause or contribute to mitochondrial dysfunction and some of the top supplements that can help mitochondria work better.
Dr. Pamela Frank, ND | Naturopath | Toronto, Ontario - Toronto Naturopath for Hormone and Digestive Health
SARS-CoV-2 can cause lasting damage to cellsβ energy production
SARS-CoV-2, the virus that causes COVID-19, can cause lasting damage to energy production by mitochondria in many organs of the body.
National Institutes of Health (NIH)