Longer Internal Exons Tend to Have More Tandem Repeats and Experience Insertions and Deletions More Frequently

#Indels #IntrinsicallyDisorderedRegions #IDRs #TandemRepeats #Preprint

https://www.biorxiv.org/content/10.1101/2024.11.03.621752v1

#InDels reshape #coenzyme specificity in #Rossmann #fold #enzymes from NAD-binding to SAM-binding

https://www.pnas.org/doi/10.1073/pnas.2207965119

#proteinengineering #proteinevolution #catalysis #moleculardynamics #xraycrystallography #PNAS